Table 2.
Diagnostic indices of cord plasma C-reactive protein (CRP) and interleukin-6 (IL-6) in the identification of a positive amniotic fluid culture, neonatal sepsis and funisitisa.
| Parameters | Sensitivity | Specificity |
|---|---|---|
|
| ||
| Amniotic fluid infection | ||
| CRP | 52% (23/44) | 76% (82/108) |
| IL-6 | 57% (25/44) | 73% (79/108) |
| Neonatal sepsis | ||
| CRP | 82% (9/11) | 74% (209/281) |
| IL-6 | 82% (9/11) | 69% (192/279) |
| Funisitis | ||
| CRP | 62% (47/76) | 83% (191/231) |
| I L-6 | 67% (51/76) | 76% (174/229) |
a
Modified with permission from Yoon BH, Romero R, Shim JY, Shim SS, Kim CJ, Jun JK. C-reactive protein in umbilical cord blood: a simple and widely available clinical method to assess the risk of amniotic fluid infection and funisitis. J Matern Fetal Neonatal Med. 2003; 14:85–90.