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. 2023 Nov;39(11):954–968. doi: 10.1016/j.pt.2023.08.007

Table I.

Minimum sample size required to detect at least one copy of a variant for a range of prevalence and power assumptions

Power Prevalence of variant in population
0.1% 0.2% 0.5% 1% 2% 5% 10%
70% 1204 602 241 120 60 24 12
80% 1609 804 322 161 80 32 16
90% 2302 1151 460 230 114 45 22