Table 2:
TMB class (no. of background mutations) | No. of samples (with kataegis) | No. of kataegis loci | No. of variants in kataegis loci |
---|---|---|---|
0.1 (25) | 128 (64) | 176 | 4,005 |
0.5 (125) | 128 (64) | 176 | 4,006 |
1 (249) | 128 (64) | 176 | 4006 |
5 (1,246) | 128 (64) | 176 | 4,014 |
10 (2,493) | 128 (64) | 176 | 4,029 |
50 (12,463) | 128 (64) | 176 | 4,077 |
100 (24,925) | 128 (64) | 176 | 4,183 |
500 (124,625) | 128 (64) | 176 | 4,925 |
Showing, per tumor mutational burden (TMB) class: TMB, number of generated background mutations per sample, the total number of samples, total number of samples with kataegis, total number of kataegis loci, and total number of variants within a kataegis loci of 1,024 synthetic samples.