Figure 2.
Time–concentration profiles of TAF, SOF, and their metabolites (TFV, TFV-DP, SOF-MP, and SOF-TP) after incubation with Huh-7, Calu-3, A549, Caco-2, and Vero-E6 cells. The intracellular concentrations were measured at 6, 12, and 24 h following incubation with 10 μM of the prodrugs. Data are presented as the mean ± SD of four independent experiments.