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. 2023 Jul 6;6(10):1340–1346. doi: 10.1021/acsptsci.3c00050

Figure 2.

Figure 2

Time–concentration profiles of TAF, SOF, and their metabolites (TFV, TFV-DP, SOF-MP, and SOF-TP) after incubation with Huh-7, Calu-3, A549, Caco-2, and Vero-E6 cells. The intracellular concentrations were measured at 6, 12, and 24 h following incubation with 10 μM of the prodrugs. Data are presented as the mean ± SD of four independent experiments.