FIG. 3.

Mosaic structure of pbp1a genes from PRSP. Regions of the sequence coding for conserved amino acid sequences are marked. Shading indicates blocks where the sequences differ from that for the PSSP R6 strain (white area) by 6% or more, i.e., blocks a to e. Groups are as follows: group I, strains 5/H31, 8/Z2, 11/Z20, 12/Z21, and variant 22/HA5; group II, strains 17/Z46, 20/B98, and 27/SHA3; group III, strains 2/H26, 4/H29, 13/Z34, 18/B43, 19/B90, 21/B99, 28/H0, 3/H28, 6/KU126, 15/Z12, 16/Z13, and variant 7/KK133; group IV, strains 14/Z42; group V, strains 23/HSB21, 24/TJ25, 26/TJ29, and variant 9/Z17.