Fig 4.

Maximum-likelihood phylogeny of 664 Shenzhen gonococcal isolates, 34 previously reported FC428 clones, and WHO-F. The maximum-likelihood phylogeny was constructed based on 46,305 SNP sites along the whole genome. The external color trips that range from inner to outer are as follows: trip 1, previously reported FC428 clones; trip 2, any mosaic penA alleles; trip 3, ceftriaxone MIC; trip 4, susceptibility categories of ceftriaxone (R, resistant; S, susceptible); trip 5, azithromycin MIC; trip 6, susceptibility categories of azithromycin (R, resistant; S, susceptible); trip 7, predominant NG-STAR STs; trip 8, predominant MLST STs. The percentages of Cro-R and Azi-R in FC428 subclade and A2543 subclade are represented by pie charts.