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. 1964 Mar;12(2):138–140. doi: 10.1128/am.12.2.138-140.1964

Microbial Hydroxylation of Indole Alkaloids

R E Hartman 1,1, E F Krause 1,2, W W Andres 1, E L Patterson 1
PMCID: PMC1058083  PMID: 14131361

Abstract

The hydroxylation of the indole-type alkaloids, yohimbine, α-yohimbine, β-yohimbine, and corynanthine, was achieved with several genera of higher fungi and species of Streptomyces. Microorganisms were found which monohydroxylated these compounds in three different positions. The site of hydroxylation was strain-specific for two strains of Cunninghamella echinulata and C. bainieri.

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Selected References

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