Fig 1.

Time-kill curves of exebacase and vancomycin against MRSA in CAMHB-HSD media. Strains MW2, CFS-2718, and CFS-2720 were treated with exebacase (A, C, and E, respectively) or vancomycin (B, D, and F, respectively). Treatment groups include the following: black, vehicle control; green, 0.25 × MIC; yellow, 0.5 × MIC; red, 1 × MIC; blue, 2 × MIC; gray, 4 × MIC; and orange, 8 × MIC. For each strain, the exebacase MIC is 0.5 µg/mL, and the vancomycin MIC is 1 µg/mL. Analyses were performed in duplicate, and mean values are indicated (±standard deviation).