Time-kill curves of exebacase and oxacillin against MSSA in CAMHB-HSD media. Strains ATCC 29213, CFS-2705, and CFS-2708 treated with exebacase (A, C, and E, respectively) and oxacillin (B, D, and F, respectively). Treatment groups include the following: black, vehicle control; green, 0.25 × MIC; yellow, 0.5 × MIC; red, 1 × MIC; blue, 2 × MIC; gray, 4 × MIC; and orange, 8 × MIC. For each strain, the exebacase MIC is 0.5 µg/mL, and the oxacillin MIC is 0.5 µg/mL. Analyses were performed in duplicate, and mean values are indicated (±standard deviation).