Box 3. Recommendations on the in-vitro diagnostics of sIgE against Hymenoptera venoms and their components.

	Strength of consensus
7. A determination of specific IgE antibodies against bee and/or Vespula venom/components shall be performed; in case of a suspected sting reaction caused by other Hymenoptera, this determination shall be also directed against the corresponding other venom.	Strong
8. In the case of negative test results obtained shortly (less than 2 weeks) after the sting reaction, the tests shall be repeated (no sooner than 4 – 6 weeks after the sting reaction).	Strong
9. In case of double sensitization against whole bee and Vespula venom extract, or if an implausible result is suspected, testing of sIgE against recombinant components shall be performed.	Strong