Table 11.
The most important genes based on the number of studies performed and the miRNAs that target them.
| Targets | miRNA | Total number of studies reporting this relationship |
|---|---|---|
| PTEN | miR-10a, miR-29b, miR-92a, miR-200a, miR-200b, miR-429, miR-216a, miR-19b, miR-106a, miR-20a, miR-200c, miR-205, miR-18b, miR-552 | 16 |
| ZEB1 | miR-211, miR-200b, miR-21, miR-126, miR-641, miR-3666, miR-484, miR-205, miR-101, miR-1236, miR-150 | 11 |
| ZEB2 | miR-200b, miR-377, miR-141, miR-101, miR-200c | 6 |
| HMGA2 | miR-302a, miR-367, miR-219, miR-145, miR-let-7 | 5 |
| MACC1 | miR-877, miR-485, miR-338 | 5 |
| TIMP2 | miR-20a, miR-492, miR-130a, miR-200b, miR-616 | 5 |
| TWIST1 | miR-326, miR-543, miR-214, miR-106b, miR-532 | 5 |
| MMP-9 | miR-183, miR-200b, miR-146b | 4 |
| Tiam1 | miR-10b, miR-183, miR-22, miR-31 | 4 |
| EGFR | miR-2861, miR-133a, miR-574, miR-7 | 4 |
| LVSI | miR-23b, miR-34c, miR-23c | 4 |
| NOB1 | miR-139, miR-612, miR-215, miR-363 | 4 |
| mTOR | miR-99b, miR-99a | 4 |
| FOXM1 | miR-320, miR-197, miR-374b | 3 |
| HOXA10 | miR-139, miR-665, miR-135a | 3 |
| IGF1R | miR-205, miR-494, miR-217 | 3 |
| MTA1 | miR-30c | 3 |
| IGF2BP1 | miR-124, miR-140, miR-708 | 3 |
| HDGF | miR-195, miR-837, miR-139 | 3 |
| SMAD2 | miR-212, miR-132, miR-484 | 3 |
| SMAD4 | miR-145, miR-205 | 3 |
| DCUN1D1 | miR-302, miR-195, miR-218 | 3 |
| MMSET | miR-34a, miR-424, miR-513 | 3 |
| STAT3 | miR-125a, miR-411, miR-20a | 3 |
| FOXA2 | miR-141, miR-200a, miR-590 | 3 |
| FAK | miR-7, miR-543 | 3 |
| hTERT | miR-138, miR-491, miR-1182 | 3 |
| c-Met | miR-23b, miR-1, miR-206 | 3 |
| ITGB1 | miR-183, miR-17 | 2 |
| YAP1 | miR-15a, miR-509 | 2 |
| HIF-1α | miR-138, miR-199a | 2 |
| HMGB3 | miR-758, miR-785 | 2 |
| HMGB1 | miR-34a, miR-142 | 2 |
| MAPK1 | miR-329, miR-320 | 2 |
| FOXC1 | miR-374c, miR-204 | 2 |
| FGF2 | miR-202, miR-936 | 2 |
| p53 | VTRNA2-1, miR-214 | 2 |
| ezrin | miR-183, miR-22 | 2 |
| MMP9 | miR-126, miR-128 | 2 |
| MMP-2 | miR-146b, miR-29b | 2 |
| S1PR1 | miR-455, miR-148a | 2 |
| TIAM1 | miR-1271, miR-22 | 2 |
| TCF12 | miR-204, miR-26a | 2 |
| Snail | miR-137, miR-34a | 2 |
| Smad7 | miR-519d, miR-519d | 2 |
| SOX9 | miR-215, miR-34c | 2 |
| SOX4 | miR-195, miR-138 | 2 |
| SIK2 | miR-874, miR-874 | 2 |
| RECK | miR-93, miR-200a | 2 |
| MMP2 | miR-126, miR-130a | 2 |
| eIF4E | miR-320a, miR-340 | 2 |
| PDE7A | miR-133a, miR-1 | 2 |
| NF-κB | miR-218, miR-218 | 2 |
| MTDH | miR-433, miR-145 | 2 |
| MSI-2 | miR-143, miR-107 | 2 |
| TIMP3 | miR-221, miR-222 | 2 |
| MMP7 | miR-543, miR-508 | 2 |
| DLC-1 | miR-141, miR-200a | 2 |
| β-catenin | miR-574, miR-638 | 2 |
| BTG3 | miR-93, miR-20a | 2 |
| CTGF | miR-133b, miR-143 | 2 |
| CCNG1 | miR-488, miR-23b | 2 |
| Bcl-2 | miR-218, miR-744 | 2 |
| CCND1 | miR-2861, miR-142 | 2 |
| BIRC5 | miR-218, miR-203 | 2 |