Table 4.

Overall Survival of HCC Cases in Relation to Different Demographic Data, Laboratory Investigations, and Tumor Characteristics

Variables		Mean Survival		Log Rank	P value
		Value	95% CI
Age	<60	19.83	17.17–22.5
	≥60	21.5	19.89–23.11	1.09	0.30
Sex	Male	20.54	17.88–23.6
	Female	Censored	–	1.74	0.19
Smoking	Yes	21.29	19.46–23.12
	No	20.35	18.07–22.62	0.61	0.44
BMI	<25	21.67	19.88–23.45
	≥25	20.28	18.19–22.37	0.20	0.66
Jaundice	Yes	6.0	6–6
	No	21.35	20.03–22.66	59.0	<0.001*
History of bilharziasis	Yes	20.38	18.47–22.28
	No	21.56	19.37–23.76	1.41	0.24
ALT	<40	21.5	19.89–23.11
	≥40	19.83	17.17–22.50	1.09	0.30
AST	<40	21.8	20.12–23.49
	≥40	19.87	17.55–22.18	1.45	0.22
Serum albumin	≥3.5	20.64	18.97–22.3
	<3.5	21.38	18.44–24.31	0.50	0.48
Total bilirubin	≤ 1.2	21.31	19.55–23.07
	>1.2	20.29	17.93–22.64	0.20	0.66
Alpha-fetoprotein	≤ 400	21.26	19.67–22.86
	>400	19.43	16.18–22.68	2.52	0.13
Ascites	Yes	22.5	20.7–24.3
	No	20.58	18.93–22.22	0.05	0.82
Child-Pugh	A	21.32	19.74–22.89
	B	19.5	16.30–22.70	1.39	0.24
BCLC	B	22.74	21.41–24.06
	C	17.55	14.81–20.28	13.81	<0.001*
Tumor number	Single	19.27	16.42–22.13
	Multiple	21.74	20.22–23.25	2.09	0.15
Tumor size	<5cm	21.39	19.76–23.01
	>5cm	19.81	17.02–22.60	2.32	0.13
Tumor site	Unilobar	21.17	19.61–22.72
	Both lobes	19.5	15.87–23.13	0.40	0.53
LN metastasis	No	21.83	20.36–23.30
	Yes	16.83	13.40–20.27	11.86	0.001*
Vascular invasion	Yes	19.33	15.54–23.12
	No	21.21	19.68–22.74	0.47	0.49
TNM staging	Stage (I&II)	21.0	18.06–23.94
	Stage (III &IV)	20.77	19.11–22.44	0.01	0.92

Notes: *Statistically significant at p ≤ 0.05.