TABLE 4.
Synergetic effect of subMICs RP557 and carbapenems against carbapenem-resistant Pseudomonas aeruginosa
| Pseudomonas aeruginosa strain | MIC (μg/mL) of combined use with RP557 (initial MIC) | ||
|---|---|---|---|
| Ertapenem | Imipenem | Meropenem | |
| ATCC 27853 | 2 (4) | 1 (4) | 0.5 (0.5) |
| NCCP 16079 | >256 (>2,048) | 32 (256) | >256 (>2,048) |
| D7 | 16 (128) | 16 (64) | 8 (32) |
| D16 | 16 (128) | 16 (64) | 8 (32) |
| D25 | 16 (256) | 16 (256) | 4 (32) |
| D26 | 16 (256) | 16 (64) | 4 (64) |
| B4 | 16 (128) | 16 (128) | 8 (32) |