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. 2023 Jul 13;248(12):1056–1073. doi: 10.1177/15353702231171900

Table 1.

M1/M2 signature genes of macrophages.

Types of macrophages Signature genes
M1 IL1B, IL1A, TNF, IL6, CXCL9, CXCL10, IL12A, IL12B, IL23A, FCGR1A, FCGR1B, FCGR1C, CCR7, IL8, CCL5, HLA-DRA, IRF5, IRF1
M2 IL10, CD163, MARCO, MRC1, MSR1, ARG1, STAB1, TGM2, MMP7, MMP9, MMP19, TGFB1, TGFB2, TGFB3, VEGFA, FN1, CCL4, CCL22, CCL17, CCL18, IL4R, IL7R, IRF4