TABLE 1.
KEGG pathway enrichment analysis of genes in co-expression modules
| Module | KEGG ID | Pathway | Count | P-value |
|---|---|---|---|---|
| Greenyellow | fgr03420 | Nucleotide excision repair | 16 | 2.75E−07 |
| fgr03440 | Homologous recombination | 9 | 2.49E−06 | |
| fgr03450 | Non-homologous end-joining | 5 | 4.13E−04 | |
| fgr03022 | Basal transcription factors | 10 | 7.21E−04 | |
| fgr00400 | Phenylalanine, tyrosine, and tryptophan biosynthesis | 9 | 7.90E−04 | |
| fgr03410 | Base excision repair | 8 | 8.08E−04 | |
| fgr01230 | Biosynthesis of amino acids | 25 | 1.04E−03 | |
| fgr04141 | Protein processing in endoplasmic reticulum | 15 | 9.63E−03 | |
| fgr03013 | RNA transport | 16 | 1.04E−02 | |
| fgr03430 | Mismatch repair | 6 | 1.39E−02 | |
| fgr02010 | ABC transporters | 8 | 1.59E−02 | |
| fgr04136 | Autophagy | 6 | 1.75E−02 | |
| fgr03050 | Proteasome | 8 | 1.89E−02 | |
| fgr04120 | Ubiquitin-mediated proteolysis | 10 | 3.33E−02 | |
| fgr04138 | Autophagy | 12 | 3.36E−02 | |
| Lightcyan | fgr01100 | Metabolic pathways | 39 | 4.95E−07 |
| fgr00260 | Glycine, serine, and threonine metabolism | 5 | 6.17E−03 | |
| fgr00600 | Sphingolipid metabolism | 3 | 1.31E−02 | |
| fgr00430 | Taurine and hypotaurine metabolism | 2 | 1.70E−02 | |
| fgr00100 | Steroid biosynthesis | 3 | 1.75E−02 | |
| fgr00230 | Purine metabolism | 4 | 2.31E−02 | |
| fgr01110 | Biosynthesis of secondary metabolites | 15 | 2.71E−02 | |
| fgr00250 | Alanine, aspartate, and glutamate metabolism | 3 | 4.50E−02 | |
| Purple | fgr00190 | Oxidative phosphorylation | 21 | 1.21E−09 |
| fgr04011 | MAPK a signaling pathway | 13 | 9.82E−06 | |
| fgr01100 | Metabolic pathways | 82 | 2.16E−05 | |
| fgr00020 | Tricarboxylic acid cycle | 7 | 8.67E−04 | |
| fgr01040 | Biosynthesis of unsaturated fatty acids | 4 | 2.84E−03 | |
| fgr01212 | Fatty acid metabolism | 7 | 5.63E−03 | |
| fgr04139 | Mitophagy | 5 | 2.09E−02 | |
| fgr04933 | AGE-RAGE signaling pathway in diabetic complications | 3 | 2.85E−02 | |
| fgr04113 | Meiosis | 7 | 4.42E−02 |
MAPK: mitogen activated protein kinase