TABLE 2.
Antimicrobial susceptibility of the 15 NDM-KP isolates in the study
| Strain | NDM type | ST | MIC (mg/L) a | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FEP | CAZ | AMC | AK | CIP | IPM | MEM | ETP | TGC | CST | CZA | |||
| ZRY2400 | NDM-1 | 152 | >128 | >128 | >128 | >128 | 8 | >128 | >128 | >128 | 0.25 | 0.25 | >128/4 |
| NB0030 | NDM-1 | 45 | >128 | >128 | >128 | 8 | 16 | >128 | >128 | >128 | 2 | 0.5 | >128/4 |
| NB0011 | NDM-1 | 3303 | >128 | >128 | >128 | 2 | 2 | >128 | >128 | >128 | 0.25 | 0.25 | >128/4 |
| NB0010 | NDM-1 | 12 | >128 | >128 | >128 | 8 | 4 | >128 | >128 | >128 | 1 | 0.5 | >128/4 |
| NB1827 | NDM-5 | 1 | >128 | >128 | >128 | 0.5 | >128 | >128 | >128 | >128 | 1 | 0.5 | >128/4 |
| ZRY3974 | NDM-5 | 17 | >128 | >128 | >128 | 1 | >128 | >128 | >128 | >128 | 0.5 | 1 | >128/4 |
| ZRY3951 | NDM-5 | 17 | >128 | >128 | >128 | 2 | 32 | >128 | >128 | >128 | 0.5 | 2 | >128/4 |
| ZRY4277 | NDM-5 | 17 | >128 | >128 | >128 | 2 | 32 | >128 | >128 | >128 | 0.5 | 0.5 | >128/4 |
| ZRY4810 | NDM-5 | 17 | >128 | >128 | >128 | 2 | 32 | >128 | >128 | >128 | 1 | 0.5 | >128/4 |
| ZRY5867 | NDM-5 | 1326 | >128 | >128 | >128 | 2 | 4 | >128 | >128 | >128 | 0.5 | 0.25 | >128/4 |
| ZRY1178 | NDM-5 | 37 | >128 | >128 | >128 | 0.5 | 64 | >128 | >128 | >128 | 4 | 0.5 | >128/4 |
| ZRY9668 | NDM-5 | 17 | >128 | >128 | >128 | 8 | 2 | >128 | >128 | >128 | 0.25 | 1 | >128/4 |
| ZRY2312 | NDM-5 | 17 | >128 | >128 | >128 | 4 | 2 | >128 | >128 | >128 | 0.5 | 0.25 | >128/4 |
| ZRY4942 | NDM-5 | 15 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | 1 | 0.25 | >128/4 |
| NB0045 | NDM-5 | 5837 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | 0.25 | 0.25 | >128/4 |
| ZRY2400J53 | – b | – | 64 | >128 | >128 | 16 | ≤0.125 | 64 | 64 | >128 | ≤0.0625 | 0.25 | >128/4 |
| NB1827J53 | – | – | >128 | >128 | >128 | 8 | ≤0.125 | >128 | >128 | >128 | 0.0625 | 0.25 | >128/4 |
| J53 | – | – | ≤0.125 | ≤0.125 | 2 | 1 | ≤0.125 | 0.5 | 0.25 | ≤0.125 | ≤0.0625 | 0.25 | 0.125 |
a
FEP, cefepime; CAZ, ceftazidime; AMC, amoxicillin-clavulanic acid; AK, amikacin; CIP, ciprofloxacin; IPM, imipenem; MEM, meropenem; ETP, ertapenem; TGC, tigecycline; CST, colistin; CZA, ceftazidime/avibactam.
b
–, not applicable.