TABLE 6.
Gene-environmental interactions between RV-C and CDHR3 SNPs on requirement for oxygen supplement b
| Number of factors | Combination | CVC | TA (%) | P value a |
|---|---|---|---|---|
| 1 | RV-C | 10 c | 67.95 | <0.001 |
| 2 | RV-C, rs3887998 | 10 | 68.92 | <0.001 |
| 3 | RV-C, rs3887998, rs408223 | 5 | 68.38 | <0.001 |
| 4 | RV-C, rs3887998, rs140154310, rs408223 | 4 | 69.98 | <0.001 |
| 5 | RV-C, rs3887998, rs4730125, rs73195665, rs408223 | 4 | 62.61 | 0.003 |
| 6 | RV-C, rs3887998, rs140154310, rs4730125, rs73195665, rs408223 | 5 | 63.91 | 0.001 |
| 7 | RV-C, rs3887998, rs73195657, rs4730125, rs6967330, rs73195665, rs408223 | 7 | 62.11 | 0.004 |
| 8 | RV-C, rs3887998, rs140154310, rs73195657, rs4730125, rs6967330, rs73195665, rs408223 | 10 | 62.24 | 0.005 |
| 9 | RV-C, rs3887998, rs140154310, rs73195657, rs146004234, rs4730125, rs6967330, rs73195665, rs408223 | 10 | 61.07 | 0.006 |
a
Adjusted for age and sex as covariates.
b
CVC, cross-validation consistency; SNP, single-nucleotide polymorphism; TA, testing accuracy.
c
Statistically significant results are highlighted in bold.