TABLE 7.
Gene-environmental interactions between RV-C and CDHR3 SNPs on systemic corticosteroid treatment b
Number of factors | Combination | CVC | TA (%) | P value a |
---|---|---|---|---|
1 | RV-C | 10 c | 71.86 | <0.001 |
2 | RV-C, rs73195657 | 7 | 71.60 | <0.001 |
3 | RV-C, rs73195657, rs4730125 | 5 | 71.51 | <0.001 |
4 | RV-C, rs3887998, rs73195657, rs4730125 | 10 | 72.67 | <0.001 |
5 | RV-C, rs3887998, rs73195657, rs4730125, rs73195665 | 8 | 69.34 | <0.001 |
6 | RV-C, rs3887998, rs73195657, rs4730125, rs6967330, rs73195665 | 8 | 69.27 | <0.001 |
7 | RV-C, rs3887998, rs140154310, rs73195657, rs4730125, rs6967330, rs73195665 | 7 | 69.58 | <0.001 |
8 | RV-C, rs3887998, rs140154310, rs73195657, rs4730125, rs6967330, rs73195665, rs408223 | 8 | 67.15 | <0.001 |
9 | RV-C, rs3887998, rs140154310, rs73195657, rs146004234, rs4730125, rs6967330, rs73195665, rs408223 | 10 | 64.41 | <0.001 |
Adjusted for age and sex as covariates.
CVC, cross-validation consistency; SNP, single-nucleotide polymorphism; TA, testing accuracy.
Statistically significant results are highlighted in bold.