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. 2023 Sep 26;11(5):e01181-23. doi: 10.1128/spectrum.01181-23

TABLE 7.

Gene-environmental interactions between RV-C and CDHR3 SNPs on systemic corticosteroid treatment b

Number of factors Combination CVC TA (%) P value a
1 RV-C 10 c 71.86 <0.001
2 RV-C, rs73195657 7 71.60 <0.001
3 RV-C, rs73195657, rs4730125 5 71.51 <0.001
4 RV-C, rs3887998, rs73195657, rs4730125 10 72.67 <0.001
5 RV-C, rs3887998, rs73195657, rs4730125, rs73195665 8 69.34 <0.001
6 RV-C, rs3887998, rs73195657, rs4730125, rs6967330, rs73195665 8 69.27 <0.001
7 RV-C, rs3887998, rs140154310, rs73195657, rs4730125, rs6967330, rs73195665 7 69.58 <0.001
8 RV-C, rs3887998, rs140154310, rs73195657, rs4730125, rs6967330, rs73195665, rs408223 8 67.15 <0.001
9 RV-C, rs3887998, rs140154310, rs73195657, rs146004234, rs4730125, rs6967330, rs73195665, rs408223 10 64.41 <0.001
a

Adjusted for age and sex as covariates.

b

CVC, cross-validation consistency; SNP, single-nucleotide polymorphism; TA, testing accuracy.

c

Statistically significant results are highlighted in bold.