Table 3.
Blood gas immediately before and after bicarbonate administration.
| Before (n = 53) | After (n = 23) | Median Difference (95% CI) | p value | |
|---|---|---|---|---|
| Hours between blood gas and bicarbonate use | −2.8 (−4.0–−1.3) | 0.6 (0.3–1.2) | 3.45 (2.67–4.23) | <0.001 |
| Sample | 0.020 | |||
| Arterial | 20 (37.7) | 16 (69.6) | ||
| Venous | 31 (58.5) | 6 (26.1) | ||
| Unknown | 2 (3.8) | 1 (4.3) | ||
| pH | 7.09 (6.94–7.19) | 7.07 (7.00–7.17) | −0.02 (−0.09 to 0.05) | 0.597 |
| Base excess, mmol/L | −20.0 (−26.6–−16.3) | −22.2 (−26.5–−16.8) | −2.20 (−6.07 to 1.66) | 0.267 |
| PaCO2, mmHg | 31.0 (25.0–35.0) | 30.0 (21.0–35.0) | −1.00 (−7.51 to 5.51) | 0.764 |
| Bicarbonate, mmol/L | 9.0 (6.0–12.0) | 8.0 (5.0–11.5) | −1.00 (−3.90 to 1.90) | 0.502 |
| Sodium, mmol/L | 134.0 (129.0–139.0) | 137.0 (133.5–141.5) | 3.00 (−0.67 to 6.67) | 0.114 |
| Potassium, mmol/L | 5.2 (4.1–6.6) | 5.2 (4.0–5.8) | −0.04 (−0.93 to 0.85) | 0.930 |
| Chloride, mmol/L | 104.0 (98.0–111.5) | 103.0 (98.5–112.5) | −1.00 (−6.87 to 4.87) | 0.739 |
| Ionised calcium | 1.2 (1.1–1.3) | 1.2 (1.0–1.3) | 0.02 (−0.12 to 0.15) | 0.822 |
| Haemoglobin, g/L | 108.0 (92.0–126.8) | 89.0 (77.8–108.2) | −17.86 (−31.91 to −3.80) | 0.015 |
| Glucose, mmol/L | 8.7 (6.7–14.7) | 14.8 (7.5–24.1) | 6.28 (−0.01 to 12.58) | 0.054 |
| Lactate, mmol/L | 7.8 (2.3–13.6) | 8.3 (1.9–17.5) | 0.50 (−6.79 to 7.79) | 0.893 |
Data are median (quartile 25th - quartile 75th) or N (%).