Table 2.

Primary, secondary, and tertiary outcome measures.

Primary outcome

•Number of days alive and free of ICU at day 60

Secondary outcomes

•In-hospital mortality

•ICU mortality

•Hospital length of stay

•ICU length of stay

•Duration of mechanical ventilation

•Mortality at 6 months

•Disability at 6 months measured with the World Health Organization's Disability Assessment Schedule 2.0 12 L

•Quality of life measured at 6 months with the Euroquol 5 questionnaire

•Neurocognitive function assessed at 6 months with the Montreal Cognitive Outcomes Assessment

•Functional outcomes as assessed using the Modified Rankin Score

Tertiary outcomes

•Cost-effectiveness

ICU: intensive care unit.