Table 3.
Histopathological correlation of study groups with immunoexpression of p53 and survivin co-expression
Characteristics | Study groups | Parameters | Survivin and p53 immunoexpression |
P | |||
---|---|---|---|---|---|---|---|
P53+/Survivin+ | P53+/Survivin- | P53-/Survivin+ | P53-/Survivin- | ||||
Histopathological grade | Group I (OPMD) (n=30) | Mild (n=10) | 10 (33.3%) | 0 (0%) | 0 (0%) | 0 (0%) | 0.000 (HS) |
Moderate (n=10) | 7 (23.3%) | 0 (0%) | 3 (10%) | 0 (0%) | 0.000 (HS) | ||
Severe (n=10) | 9 (30%) | 0 (0%) | 0 (0%) | 1 (3.3%) | 0.002 (S) | ||
Group II (OSCC) (n=30) | WDSCC (n= 11) | 10 (33.3%) | 0 (0%) | 0 (0%) | 1 (3.3%) | 0.001 (S) | |
MDSCC+PDSCC (n=19) | 13 (43.3%) | 2 (6.7%) | 3 (10%) | 1 (3.3%) | 0.127 |
S: Significant, HS: Highly Significant, +: Present,-: Absent, WDSCC: Well-differentiated squamous cell carcinoma, MDSCC+PDSCC: Moderately differentiated and Poorly differentiated squamous cell carcinoma combined