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. 2023 Jul 13;27(2):287–294. doi: 10.4103/jomfp.jomfp_5_23

Table 3.

Histopathological correlation of study groups with immunoexpression of p53 and survivin co-expression

Characteristics Study groups Parameters Survivin and p53 immunoexpression
P
P53+/Survivin+ P53+/Survivin- P53-/Survivin+ P53-/Survivin-
Histopathological grade Group I (OPMD) (n=30) Mild (n=10) 10 (33.3%) 0 (0%) 0 (0%) 0 (0%) 0.000 (HS)
Moderate (n=10) 7 (23.3%) 0 (0%) 3 (10%) 0 (0%) 0.000 (HS)
Severe (n=10) 9 (30%) 0 (0%) 0 (0%) 1 (3.3%) 0.002 (S)
Group II (OSCC) (n=30) WDSCC (n= 11) 10 (33.3%) 0 (0%) 0 (0%) 1 (3.3%) 0.001 (S)
MDSCC+PDSCC (n=19) 13 (43.3%) 2 (6.7%) 3 (10%) 1 (3.3%) 0.127

S: Significant, HS: Highly Significant, +: Present,-: Absent, WDSCC: Well-differentiated squamous cell carcinoma, MDSCC+PDSCC: Moderately differentiated and Poorly differentiated squamous cell carcinoma combined