Table 4.
Correlation of p53 immunoexpression with survivin immunoexpression in Group I (OPMD)
| Parameters | p53 Expression |
p53 Intensity |
p53 Topography |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Absent | Present | Absent | Weak | Moderate | Strong | Absent | B | B+SB | B+SB+SUP | ||
| Survivin Immunolocalization | Absent | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Nuclear | 2 | 16 | 2 | 8 | 5 | 3 | 2 | 11 | 5 | 0 | |
| Cytoplasmic | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Both | 1 | 10 | 1 | 7 | 0 | 3 | 1 | 4 | 5 | 1 | |
| P | 0.03 (S) | 0.095 | 0.128 | ||||||||
| Survivin Intensity | Weak | 0 | 2 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
| Moderate | 2 | 7 | 2 | 4 | 2 | 1 | 2 | 6 | 1 | 0 | |
| Strong | 1 | 17 | 1 | 10 | 3 | 4 | 1 | 8 | 8 | 1 | |
| P | 0.02 (S) | 0.344 | 0.241 | ||||||||
| Survivin Topography | Basal | 0 | 9 | 0 | 5 | 2 | 2 | 0 | 7 | 2 | 0 |
| B+SB | 2 | 8 | 2 | 5 | 1 | 2 | 2 | 5 | 3 | 0 | |
| B+SB+SUP | 1 | 9 | 1 | 5 | 2 | 2 | 1 | 3 | 5 | 1 | |
| P | 0.04 (S) | 0.466 | 0.142 | ||||||||
S: Significant