Table 5.
Correlation of p53 immunoexpression with Survivin immunoexpression in Group II (OSCC)
| Parameters | p53 expression |
p53 Intensity |
p53 Topography |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Absent | Present | Absent | Weak | Moderate | Strong | Absent | Peripheral | Central | Both | ||
| Survivin Immunolocalization | Absent | 2 | 2 | 2 | 0 | 2 | 0 | 2 | 2 | 0 | 0 |
| Nuclear | 2 | 6 | 2 | 2 | 0 | 4 | 2 | 5 | 0 | 1 | |
| Cytoplasmic | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Both | 1 | 17 | 1 | 7 | 2 | 8 | 1 | 12 | 0 | 5 | |
| P | 0.07 | 0.04 (S) | 0.196 | ||||||||
| Survivin Intensity | Weak | 0 | 9 | 0 | 2 | 2 | 5 | 0 | 6 | 0 | 3 |
| Moderate | 1 | 4 | 1 | 0 | 0 | 4 | 1 | 2 | 0 | 2 | |
| Strong | 2 | 10 | 2 | 7 | 0 | 3 | 2 | 9 | 0 | 1 | |
| P | 0.169 | 0.009 | 0.208 | ||||||||
| Survivin Topography | Peripheral | 0 | 17 | 0 | 6 | 2 | 9 | 0 | 13 | 0 | 4 |
| Central | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Both | 3 | 6 | 3 | 3 | 0 | 3 | 3 | 4 | 0 | 2 | |
| P | 0.01 (S) | 0.02 (S) | 0.061 | ||||||||
S: Significant