Table 2.
Isoxazolines currently available for use in cats in Canada.
| Product name (market year) | Manufacturer | Route of administration | Isoxazoline | Macrocyclic lactone | Other | Labelled use | Extra-label use |
|---|---|---|---|---|---|---|---|
| Bravecto topical solution (2017) | Merck/Intervet | Topical | Fluralaner | N/A | N/A | F, T | D, O |
| Credelio cat (2022) | Elanco | Oral | Lotilaner | N/A | N/A | F, T | |
| NexGard combo (2022) | Boehringer Ingelheim | Topical | Esafoxolaner | Eprinomectin | Praziquantel | F, T, R, TP, HT, O | L, N |
| Revolution plus (2019) | Zoetis | Topical | Sarolaner | Selamectin | N/A | F, T, R, HK, HT, O | D |
| Vitrecto topical solution (2020) | Merck/Intervet | Topical | Fluralaner | Moxidectin | N/A | F, T, R, HK, HT |
D — Demodicosis; F — Fleas; HK — Hookworm; HT — Heartworm; L — Lice infestation; N — Notoedric mange (scabies); N/A — Not available; O — Otodectic mange; R — Roundworm; T — Ticks; TP — Tapeworm.