Table 3.
Feline demodicosis: Fluralaner and sarolaner studies.
| Reference (year) | Treatment protocol and outcome |
|---|---|
| 13 (2017) | Case report: 1 cat with generalized demodicosis caused by Demodex cati |
| Single oral dose of fluralaner | |
| 100% mite free at Day 30 | |
| No adverse effects | |
| 14 (2018) | Case report: 2 shelter cats (a queen and her kitten) with demodicosis caused by Demodex gatoi |
| Single oral dose of fluralaner | |
| 100% mite free at Day 30 | |
| Adverse effects not recorded | |
| 15 (2019) | Case series: 7 cats with generalized demodicosis caused by Demodex cati |
| Single topical spot-on dose of fluralaner | |
| 100% mite free at Day 14 | |
| No adverse effects | |
| 16 (2021) | Case report: 1 cat with generalized demodicosis caused by Demodex cati |
| Single topical spot-on dose of fluralaner | |
| 100% mite free at Day 7 | |
| No adverse effects | |
| 17 (2022) | Case report: 1 cat with localized demodicosis and bilateral otodemodicosis caused by Demodex cati |
| Single topical spot-on dose of fluralaner | |
| 100% mite free at Day 42 | |
| Adverse effects not recorded | |
| 18 (2019) | Case report: 2 sibling cats with demodicosis caused by Demodex gatoi |
| Monthly topical spot-on doses of sarolaner-selamectin combination | |
| Skin scrapings not repeated (personal communication) | |
| Almost complete hair regrowth 15 wk after onset of treatment | |
| Adverse effects not recorded | |
| 19 (2020) | Case report: 1 cat with generalized demodicosis caused by Demodex spp. |
| Single oral dose of sarolaner | |
| 100% mite free at Day 21 | |
| Adverse effects not recorded | |
| 20 (2021) | Case report: 1 cat with unilateral otodemodicosis caused by Demodex cati |
| 4 topical spot-on doses of sarolaner-selamectin combination, 30 d apart | |
| 100% mite free at Day 120 | |
| No adverse effects |