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. 2023 Nov;64(11):1066–1070.

Table 4.

Numbers of recommended doses of isoxazolines (use either a single isoxazoline product or a combination product).

Disease Number of doses
Canine otodectic mange 2 monthly oral doses of afoxolaner
1 oral or topical dose of fluralaner
2 monthly oral doses of sarolaner
Feline otodectic mange 1 oral dose of afoxolaner
1 topical dose of esafoxolaner or fluralaner
1 oral or topical dose of sarolaner
Feline demodicosis 1 oral or topical dose of fluralaner or sarolaner
Feline lynxacariasis 1 oral dose of fluralaner or sarolaner
Feline lice infestation 1 topical dose of esafoxolaner
Feline notoedric mange (scabies) 1 topical dose of esafoxolaner
Demodicosis in hamsters 1 oral dose of fluralaner
Sarcoptic mange in rabbits 1 oral or topical dose of fluralaner
Psoroptic mange in rabbits 1 oral dose of afoxolaner or fluralaner