Table 3.
Overview of the Assessment of the Quality of the Selected Guidelines Using the AGREE II Tool
| Domain | Guideline | |||||
|---|---|---|---|---|---|---|
| OT | RN | NICE | HD_PT | GAC | EHDN | |
| Domain 1: scope and purpose | ||||||
| 1 | 7 | 7 | 7 | 6 | 7 | 7 |
| 2 | 7 | 7 | 7 | 7 | 7 | 4.5 |
| 3 | 4 | 7 | 7 | 5.5 | 7 | 4 |
| Domain 2: stakeholder involvement | ||||||
| 4a | 4 | 6 | 7 | 6 | 6.5 | 6.5 |
| 5 | 2.5 | 2.5 | 5 | 7 | 7 | 4.5 |
| 6 | 7 | 7 | 7 | 7 | 7 | 6 |
| Domain 3: rigor of development | ||||||
| 7a | 7 | 7 | 7 | 7 | 7 | 7 |
| 8a | 7 | 7 | 7 | 7 | 7 | 5 |
| 9 | 7 | 4.5 | 7 | 7 | 7 | 6 |
| 10a | 3 | 3 | 7 | 6.5 | 7 | 6.5 |
| 11 | 5.5 | 5 | 7 | 4.5 | 6.5 | 6.5 |
| 12a | 6 | 6.5 | 7 | 7 | 7 | 7 |
| 13a | 3.5 | 6 | 7 | 7 | 6 | 5.5 |
| 14 | 5 | 7 | 7 | 7 | 7 | 1 |
| Domain 4: clarity and presentation | ||||||
| 15a | 6.5 | 7 | 7 | 6 | 6.5 | 5.5 |
| 16 | 7 | 7 | 7 | 4.5 | 7 | 7 |
| 17 | 7 | 7 | 7 | 7 | 7 | 7 |
| Domain 5: applicability | ||||||
| 18 | 7 | 5 | 1.5 | 6 | 5 | 3 |
| 19 | 7 | 7 | 7 | 5.5 | 4.5 | 1.5 |
| 20 | 6.5 | 7 | 7 | 3 | 5.5 | 1.5 |
| 21 | 2.5 | 6 | 7 | 3.5 | 6 | 2.5 |
| Domain 6: editorial independence | ||||||
| 22a | 5.5 | 6.5 | 3 | 7 | 7 | 4 |
| 23a | 3.5 | 7 | 7 | 7 | 7 | 3.5 |
| Total score of nine key items (4, 7, 8, 10, 12, 13, 15, 22, and 23) | 46 | 56 | 59 | 60.5 | 61 | 50.5 |
| Average score of total 23 items | 5.6 | 6.2 | 6.5 | 6.1 | 6.6 | 4.9 |
Notes: GAC = Guideline Adaptation Committee. Clinical Practice Guidelines and Principles of Care for People with Dementia; RN = Registered Nurses’ Association of Ontario. Delirium, Dementia, and Depression in Older Adults: Assessment and Care (2nd ed.); OT = American Occupational Therapy Association. Occupational therapy practice guidelines for adults with Alzheimer’s disease and related major neurocognitive disorders; NICE = National Institute for Health and Care Excellence. Dementia: assessment, management and support for people living with dementia and their carers; EHDN = European Huntington’s Disease Network. International Guidelines for the Treatment of Huntington’s disease; HD_PT = Clinical practice recommendations to guide physical therapy practice for Huntington’s disease.
aOne of the nine items of the Appraisal of Guidelines for Research and Evaluation (AGREE II) tool that was used for a final selection: To be included in the final list, guidelines must have an average total score of 45 or more for the nine key items across two reviewers and a minimum score of 3 for items 7, 8, 12, and 22 (bold numbers) (both reviewers independently). Scoring for each item ranges from 1 (strongly disagree) to 7 (strongly agree) and reflects “relevance” for each clinical practice guideline.