Table 3. Concentration of azaperone in the blood serum (ng/ml).
Blood collection time (min) | Groups | |||
A (2 mg/kg b.w. i.m., n = 8) | B (2 mg/kg b.w., n = 8) | C (4 mg/kg b.w., n = 8) | D (control, n = 8) | |
0 | n.d.x | n.d.x | n.d.x | n.d.x |
30 | 156.5 ± 61.5x | 77.74 ± 27.1y | 128.4 ± 52.5x | n.d.x |
90 | 75.1 ± 20.9x | 35.5 ± 14.8y | 71.3 ± 40.5x | n.d.x |
240 | 28.1 ± 6.6x | 15.8 ± 5.2y | 28.2 ± 8.3x | n.d.x |
Data are expressed as the mean ± standard deviation
Means with the same blood collection time and row lacking a common superscript letter (x, y, z) differ significantly (P < 0.05)
n.d. = non-detected – azaperone concentration below the detection limit – 0.785 ng/ml