Table 2.
Participant-reported measures at baseline
| Total (n=349) | Urinary urgency with incontinence (n=281) | Urinary urgency without incontinence (n=68) | |
|---|---|---|---|
|
| |||
| Overall LUTS tool a score ¥ | 47.7 (12.8) | 49.6 (12.6) | 39.9 (10.5) |
| LUTS tool frequency score γ | 55.8 (18.4) | 56.8 (17.8) | 51.8 (20.1) |
| LUTS tool post-micturition score β | 48.4 (26.0) | 48.9 (26.2) | 46.4 (25.0) |
| LUTS tool urgency score γ | 65.0 (18.0) | 68.5 (17.5) | 50.5 (12.5) |
| LUTS tool voiding difficulty score λ | 28.3 (21.1) | 28.7 (21.1) | 26.8 (21.3) |
| LUTS tool pain score γ | 16.3 (21.7) | 16.3 (21.5) | 16.2 (22.8) |
| LUTS tool UI score λ | 45.4 (19.3) | 50.1 (16.6) | 26.6 (17.6) |
| Quality of life due to urinary symptoms (0=delighted to 6=terrible) λ | 4.7 (1.1) | 4.8 (1.1) | 4.3 (1.2) |
| PROMIS b depression (T-score) γ | 50.4 (9.0) | 50.9 (9.1) | 48.2 (8.0) |
| PROMIS anxiety (T-score) γ | 51.4 (9.4) | 51.6 (9.6) | 50.4 (8.5) |
| PROMIS physical function (T-score) γ | 45.7 (10.4) | 45.0 (10.4) | 48.6 (10.2) |
| PROMIS sleep disturbance (T-score) γ | 51.9 (4.8) | 52.0 (4.9) | 51.4 (4.7) |
| PROMIS GI diarrhea (T-score) γ | 49.7 (9.6) | 50.0 (9.7) | 48.2 (9.5) |
| PROMIS GI constipation (T-score) λ | 52.2 (8.2) | 52.2 (8.1) | 51.9 (8.4) |
| Perceived stress scale λ | 13.7 (7.8) | 13.9 (7.7) | 12.8 (7.9) |
| PROMIS GI bowel incontinence (raw scale) λ | 5.6 (2.7) | 5.7 (2.8) | 5.2 (2.7) |
Table values are mean (standard deviation). The LUTS Tool scores range from 0 to 100 and were created by combining responses to related symptom severity questions from the LUTS Tool and calculating the Euclidean length of the relevant questions as a measure of overall symptom severity. PROMIS measures T-scores have a mean of 50 and a standard deviation of 10 in the US general population. The minimal clinically important differences is 3 to 5 points in T-scores across PROMIS measures.
β
Missing <2%
γ
Missing 2%−5%
λ
Missing 5%−10%
¥
Missing 17%
LUTS, lower urinary tract symptoms; UI, urinary incontinence; PROMIS, Patient-Reported Outcomes Measurement Information System; GI, gastrointestinal
a
LUTS Tool14
b
PROMIS17