Table 4.
C-statistic [95% CI] (0 to 1, higher is better) | Brier Score [95% CI] (0 to 1, lower is better) | |
---|---|---|
Outcome: Level of Treatment | ||
Proportional odds model | ||
Overall | 0.686 [0.657, 0.741] | NA a |
Level 1–4 vs. 0 | 0.686 [0.657, 0.742] | 0.154 [0.126, 0.175] |
Level 2–4 vs. 0–1 | 0.685 [0.658, 0.741] | 0.217 [0.193, 0.226] |
Level 3–4 vs. 0–2 | 0.686 [0.658, 0.741] | 0.162 [0.137, 0.180] |
Level 4 vs. 0–3 | 0.684 [0.656, 0.741] | 0.063 [0.040, 0.084] |
Separate binary logistic regression models | ||
Level 1–4 vs. 0 | 0.663 [0.653, 0.712] | 0.158 [0.146, 0.173] |
Level 2–4 vs. 0–1 | 0.702 [0.664, 0.779] | 0.216 [0.191, 0.226] |
Level 3–4 vs. 0–2 | 0.796 [0.762, 0.868] | 0.159 [0.127, 0.173] |
Level 4 vs. 0–3 | 0.673 [0.615, 0.863] | 0.065 [0.037, 0.084] |
Outcome: Time to OAB Medication Discontinuation | ||
Cox proportional hazard model | 0.671 [0.579, 0.766] | 0.185 [0.151, 0.247] b |
Outcome: Sling | ||
Binary logistic regression | 0.823 [0.829, 0.834] | 0.091 [0.089, 0.091] |
Note: Brier score captures both discrimination and calibration. It ranges between 0 and 1, with lower score indicating better model performance. C-statistic assess discrimination and ranges between 0 and 1, with higher score indicating better discrimination performance.
Brier score is inappropriate for ordinal outcome.
Brier score evaluated at 6-month since OAB medication initiation or baseline if medication was started before baseline. It is not corrected for bias.
CI, confidence interval; OAB, overactive bladder