Table 1. Electrophysiological properties of Id2 INs in S1BF.
Table 1—source data 1. Electrophysiological parameters source data.
This excel spreadsheet lists all of the cells patched alongside their electrophysiological parameters. The file consists of two workbooks, ‘tabulation’ containing the parameters for each cell, and ‘summary’ containing the summary data (average, sem, n) for each cell type. For some cells, no values are reported for some parameters and these cells are marked ‘n/a.’ A small number of cells were patched with an internal solution different than that reported in the methods. Electrophysiology parameters for these cells were not reported, as differences in internal solution can have significant impacts on electrophysiological parameters, but the cells were counted alongside the rest for the proportions reported in Figure 3. These cells were marked as ‘0’ in the ‘Internal’ column or ‘1’ otherwise. Several cells categorized as LS do not have a value for the AP latency as for these cells a voltage trace bearing a single AP was not obtained. Nevertheless, these cells were confidently labeled LS as the late-onset of the APs is evident even in multiple AP traces. Cells patched in slices with NPY-GFP (i.e. Id2-CreER; Dlx5/6-Flpe; Ai65; NPY-hrGFP) are not listed in this file as the parameters summarized in Table 1 were only taken from the unbiased cross (i.e. Id2-CreER; Dlx5/6-Flpe; Ai65).
elife-85893-table1-data1.xlsx (44.2KB, xlsx)
| Electrophysiological property | LS in L2/3(n≥15) | LS in L4-5(n≥5) | IS in L2/3(n≥5) | BS in L2/3(n≥5) |
|---|---|---|---|---|
| First AP latency (ms) | 805±22 | 827±32 | 53±4 | 143±37 |
| Input Resistance (MΩ) | 188±7 | 130±11*** | 199±32 | 301±32*** |
| Membrane τ (ms) | 12±0.5 | 11±0.8 | 13±1.2 | 17±1.4** |
| AP half-width (ms) | 0.70±0.02 | 0.63±0.08 | 0.48±0.04*** | 0.57±0.05* |
| AP threshold (mV) | 35±1 | 33±2 | 38±2 | 41±2* |
| AP rise slope (mV/ms) | 283±15 | 367±61 | 404±60 | 322±46 |
| AP fall slope (mV/ms) | 84±4 | 108±20 | 150±19*** | 135±29* |
| AHP amplitude (mV) | 14.4±0.5 | 12.9±1.1 | 9.9±0.9*** | 6.6±1.3*** |
| Rheobase (pA) | 139±14 | 205±44 | 155±18 | 51±7*** |
| Firing rate (Hz) (at 2 x rheobase) |
38±3 | 29±4 | 40±6 | 31±7 |
| Firing Regularity (at 2 x rheobase) |
0.053±0.004 | 0.050±0.008 | 0.112±0.029** | 0.262±0.124** |
| Adaptation Index (near rheobase) |
1.14±0.08 | 1.06±0.11 | - | - |
| Adaptation Index (at 2 x rheobase) |
0.76±0.03 | 0.72±0.03 | 0.26±0.05*** | 0.24±0.14** |