Skip to main content
. 2023 Oct 10;2023:7398724. doi: 10.1155/2023/7398724

Table 2.

Summary of bacterial reverse mutation assay results (pre-experiment I; up to 5,000 µg/plate)—mean ± SD revertant colonies.

Tester strains TA98 TA100 TA1535 TA1537 WP2 uvrA
±S9 −S9 +S9 −S9 +S9 −S9 +S9 −S9 +S9 −S9 +S9
Water 37 ± 19.2 40 ± 3.8 104 ± 5.1 104 ± 1 13 ± 0.6 9 ± 3 11 ± 2.9 13 ± 1.7 254 ± 7 279 ± 23.6
31.6 µg/plate 34 ± 2 37 ± 8.5 108 ± 4.9 105 ± 13.2 15 ± 2.1 6 ± 3.2 18 ± 1.7 13 ± 5 213 ± 36.1 242 ± 32.7
100 µg/plate 33 ± 5.7 35 ± 4.9 92 ± 9.6 108 ± 7.2 9 ± 3.2 6 ± 1.2 11 ± 1.2 10 ± 1.7 228 ± 14.6 271 ± 15.6
316 µg/plate 33 ± 7 37 ± 6.4 101 ± 17.1 95 ± 13.2 12 ± 1.5P 5 ± 1P 9 ± 3.1P 10 ± 2.5P 283 ± 1.85P 299 ± 18.6P
1000 µg/plate 42 ± 10.5P 42 ± 6.2P 90 ± 8.7P 108 ± 7.2P 9 ± 2.9P 9 ± 4.4P 11 ± 1.2P 13 ± 3.8P 277 ± 26.9P 300 ± 26.5P
2500 µg/plate 30 ± 10.4P 44 ± 8.7P 103 ± 1.7P 98 ± 7.6P 8 ± 1.2P 8 ± 1.2P 10 ± 2.5P 14 ± 5.6P 202 ± 2.6P 238 ± 30.6P
5000 µg/plate 24 ± 5.8P 45 ± 2.6P 89 ± 10P 93 ± 8.7P 5 ± 3P 6 ± 0.6P 9 ± 3.1P 9 ± 4.2P 222 ± 7.6P 265 ± 22.1P
4-NOPD (10 µg/plate) 542 ± 45 NA 432 ± 22 NA 918 ± 78.4 NA 60 ± 15.5 NA 1255 ± 61.2 NA
2-AA (2.5 µg/plate) NA 2057 ± 223.1 NA 1361 ± 19.2 NA 264 ± 10.1 NA 175 ± 11.9 NA 693 ± 125

2-AA = 2-aminoanthracene; LegH = soy leghemoglobin protein; NA = data not applicable; 4-NOPD = 4-nitro-o-phenylenediamine; P: visible precipitate; SD = standard deviation; +S9 = containing phenobarbital/B-naphthoflavone-induced Sprague–Dawley rat liver microsomal fraction; −S9 = without S9 microsomal fraction. Data are shown as mean ± SD revertants/plate for three replicates for each concentration in each experiment.