Table 3.

Receiver operating characteristic curve analyses and diagnostic performance of the evaluated scoring systems to predict in-hospital mortality in patients with Fournier gangrene

Scoring system	Cutoff score	AUROC	95% CI	p value	Sensitivity	Specificity	PPV	NPV
FGSI	> 9	0.905	0.860–0.950	< 0.001	1.0	0.81	0.65	1.0
UFGSI	≥ 9	0.788	0.714–0.862	< 0.001	0.91	0.67	0.49	0.95
SFGSI	> 2	0.642	0.540–0.743	0.006	0.47	0.82	0.48	0.81
NFS	> II	0.823	0.739–0.906	< 0.001	0.74	0.90	0.73	0.91
LRINEC	≥ 6	0.635	0.543–0.737	0.006	0.63	0.65	0.39	0.83
aCCI	≥ 4	0.721	0.644–0.816	< 0.001	0.79	0.67	0.46	0.90
SOFA	≥ 4	0.830	0.815–0.921	< 0.001	1.0	0.74	0.57	1.0
qSOFA	≥ 2	0.709	0.628–0.790	< 0.001	0.93	0.49	0.39	0.95
APACHE II	≥ 13	0.756	0.666–0.860	< 0.001	0.56	0.97	0.86	0.86
SAS	≤ 4	0.500	0.399–0.601	1.000	1.0	0.0	0.26	–

95% CI 95% confidence interval; aCCI age-adjusted Charlson comorbidity index; APACHE II acute physiology and chronic health evaluation II; AUROC area under the receiver operating characteristic curve; FGSI Fournier gangrene severity index; LRINEC laboratory risk indicator for necrotizing fasciitis; NFS NUMUNE Fournier score; NPV negative predictive value; PPV positive predictive value; qSOFA quick SOFA; SAS surgery APGAR score; SE standard error; SFGSI simplified FGSI; SOFA sequential organ failure assessment; UFGSI Uludag FGSI