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. 2023 Oct 17;11(1):49. doi: 10.1007/s13755-023-00251-w

Table 2.

Example of the algorithm for a patient with thyroid papillary cancer within a year after the last surgical operation

Risks Free T4 TSH (μIU/ml) Change of thyroxine (μg)
DTC recurrence risk high or medium (TSH target 0–0.1) (1) If it is lower than the upper bound of the normal value, the change of thyroxine is recommended according to the corresponding line 0.1–0.5 Increase by 12.5
0.5–2.0 Increase by 25.0
2.0–10 Increase by 50.0
10–30 Increase by 75.0
30–100 Increase by 100
DTC reccurence risk low & side effect risk high or medium (TSH target 0.5–1.0) 0.1–0.5 Decrease by 12.5
0.5–1.0 Unchange
1.0–5.0 Increase by 25.0
5.0–10 Increase by 50.0
10–30 Increase by 75.0
30–100 Increase by 100
0.1–0.5 Unchange
DTC reccurence risk low & side effect risk low (TSH target 0.1–0.5) (2) If it exceeds the upper bound of normal values, follow the recommendation of the previous line; If the current line is the first line, maintain the original dose 0.5–1.0 Increase by 12.5
1.0–5.0 Increase by 25.0
5.0–10 Increase by 50.0
10–30 Increase by 75.0
30–100 increase by 100