Table 3.
Demographics, clinical parameters and outcomes of ICU-admitted patients eligible for VV-ECMO by EOLIA, ELSO, NSW, CCSO and Regina-restrictive criteria.
| EOLIA criteria (n = 7) | ELSO criteria (n = 6) | NSW (n = 19) | CCSO criteria (n = 26) | Regina-restrictive criteria (n = 12) | |
|---|---|---|---|---|---|
| Criteria met, N (%) | 7 (1.7%) | 6 (1.5%) | 19 (4.6%) | 26 (6.3%) | 12 (2.9%) |
| Age, median years (IQR) | 67 (54–70) | 49 (31–69) | 63 (44–73) | 67 (54–73) | 61 (52–70) |
| Male gender, N (%) | 4 (57.1%) | 6 (100%) | 16 (84.2%) | 19 (73.1%) | 10 (83.3%) |
| Charlson Comorbidity Index, median score (IQR) | 1 (0–3) | 1.5 (1–3) | 2 (0–5) | 1 (0–2) | 1 (0–2) |
| Sequential Organ Failure Assessment, median score (IQR) | 10 (7–13) | 11 (8–13) | 8 (7–11) | 8 (5–10) | 8 (6–9) |
| Clinical Frailty Score (IQR) | 3 (2–4) | 2 (2–2) | 3 (2–3) | 3 (2–4) | 3 (3–4) |
| Body Mass Index, median kg/m2 (IQR) | 29 (26–31) | 32 (30–46) | 28 (24–32) | 30 (28–41) | 29 (27–35) |
| Need for dialysis, N (%) | 2 (28.6%) | 0 (0%) | 3 (15.8%) | 3 (11.5%) | 0 (0%) |
| COVID-19, N (%) | 1 (14.3%) | 3 (50.0%) | 2 (10.5%) | 5 (19.2%) | 4 (33.3%) |
| Set VT, median mL/kg (IQR) | 7.7 (7.4–8.2) | 7.4 (6.8–7.7) | 7.3 (7.0–7.6) | 7.8 (7.3–8.6) | 7.0 (6.0–7.9) |
| Actual delivered VT, median mL/kg (IQR) | 8.2 (8.0–8.9) | 8.7 (7.0–10.4) | 8.8 (7.2–10.2) | 8.6 (8.0–10.4) | 8.6 (6.4–10.4) |
| Prone positioning, N (%) | 3 (42.9%) | 5 (83.3%) | 9 (47.4%) | 12 (46.2%) | 7 (58.3%) |
| Neuromuscular blockade, N (%) | 4 (57.1%) | 5 (83.3%) | 10 (52.6%) | 12 (46.2%) | 8 (66.7%) |
| Nitric oxide, N (%) | 2 (28.6%) | 1 (16.7%) | 2 (10.5%) | 3 (11.5%) | 2 (16.7%) |
| Hospital length of stay, median days (IQR) | 8 (1–10) | 1 (1–9) | 12 (2–25) | 19 (10–25) | 15 (9–20) |
| ICU length of stay, median days (IQR) | 3 (1–10) | 1 (1–9) | 8 (1–13) | 13 (3–22) | 13 (9–18) |
| In-hospital mortality, N (%) | 6 (83.7%) | 5 (83.3%) | 12 (63.2%) | 14 (53.9%) | 9 (75.0%) |
CCSO Critical Care Services Ontario, COVID-19 Coronavirus-19, ELSO Extracorporeal Life Support Organization, EOLIA Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Syndrome, ICU intensive care unit, IQR interquartile range, NSW New South Wales, VT tidal volume, VV-ECMO veno-venous extracorporeal membrane oxygenation.