Table 2.
Univariate analysis | Multivariate analysis | |||||
---|---|---|---|---|---|---|
OR | 95% CI | P value | OR | 95% CI | P value | |
Gender | ||||||
Male (vs. female) | 5.20 | 2.90–9.31 | < 0.001 | 4.01 | 2.09–7.70 | < 0.001 |
Age | ||||||
Continuous | 1.05 | 1.03–1.07 | < 0.001 | 1.04 | 1.01–1.06 | 0.002 |
Stone composition | ||||||
Non-uric acid | (ref) | (ref) | ||||
Mixed-uric acid | 4.53 | 2.48–8.26 | < 0.001 | 2.73 | 1.43–5.21 | 0.002 |
Pure-uric acid | 9.72 | 5.46–17.29 | < 0.001 | 5.92 | 3.18–11.02 | < 0.001 |
NLR | ||||||
High (> 2.8 vs. ≤ 2.8) | 1.99 | 1.29–3.09 | 0.002 | 1.72 | 1.03–2.88 | 0.039 |
Overweight | ||||||
Yes (BMI > 25 vs. ≤ 25) | 1.20 | 0.77–1.86 | 0.426 | |||
DM | ||||||
Yes vs. No | 1.55 | 0.97–2.45 | 0.065 | |||
HTN | ||||||
Yes vs. No | 1.65 | 1.07–2.55 | 0.024 | |||
Gout | ||||||
Yes vs. No | 3.09 | 1.57–6.06 | 0.001 | 1.37 | 0.81–2.30 | 0.242 |
CVD | ||||||
Yes vs. No | 1.30 | 0.59–6.90 | 0.517 | |||
Hyperuricemia | ||||||
Yes (> 7 vs. ≤ 7 mg/dL) | 2.26 | 1.12–4.57 | 0.023 | |||
Dyslipidemia | ||||||
Yes vs. No | 0.80 | 0.40–1.60 | 0.524 | |||
Acidic urine | ||||||
Yes (pH < 6 vs. ≥ 6) | 1.55 | 0.99–2.42 | 0.056 |
Parameters used for multivariate regression analysis: gender, age, stone composition, NLR, HTN. OR odds ratio, CI confidence interval, DM type 2 diabetes mellitus, HTN hyper-tension, CVD cardiovascular diseases, NLR neutrophil/lymphocyte ratio.