TABLE 2.
Antichlamydial activities of monoglycerides
| Monoglycerides | Concn (mM)a | Reduction of IFU (log10) at the following times (min):
|
||
|---|---|---|---|---|
| 10 | 5 | 1 | ||
| Monocaprin (10:0) | 20 | ≥4.6b | ≥4.1b | 1.0 |
| 10 | ≥5.6c | ≥5.1c | 0.6 | |
| 5 | ≥5.6c | ≥5.1c | 0.6 | |
| Monolaurin (12:0) | 20 | 0.5 | NDd | ND |
| 10 | 0.7 | ND | ND | |
| 5 | 0.6 | ND | ND | |
a
Concentration of monoglycerides mixed with C. trachomatis and incubated at 37°C for 1, 5, and 10 min. The concentration in the mixtures was reduced by half.
b
No inclusions were detected in the 10−2 dilution, which was the lowest dilution tested.
c
No inclusions were detected in the 10−1 dilution.
d
ND, not done.