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. 2023 Oct 4;14:1233711. doi: 10.3389/fphys.2023.1233711

TABLE 1.

Activation of avian Tas2rs by bitter substances.

No. Receptor substance tgTas2r1 tgTas2r5 tgTas2r6 tgTas2r7 ggTas2r1 ggTas2r2 ggTas2r7 mgTas2r3 mgTas2r4
1 Absinthin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
2 Amarogentin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
3 Andrographolide graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg
4 Azathioprine graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
5 Caffeine graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg
6 Camphor graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg
7 Carisoprodol graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
8 Chloramphenicol graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
9 Chloroquine graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg
10 Chlorpheniramine graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg
11 Colchicine graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg
12 Coumarin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg
13 Cucurbitacin I graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg
14 Cycloheximide graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg
15 Denatoniumbenzoate graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg
16 Diphenhydramin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg
17 Diphenidol graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
18 Erythromycin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
19 Gingkolide A graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg
20 Limonin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg
21 Nicotin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
22 Parthenolide graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg
23 Picrotoxinin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
24 PTC graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg
25 Quassin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
26 Quinine sulphate graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
27 Saccharin graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg
28 (−)-α-Thujone graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx3.jpg
29 Yohimbine graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx2.jpg graphic file with name FPHYS_fphys-2023-1233711_wc_tfx1.jpg

The bitter compounds shown to activate zebra finch (tgTas2r), chicken (ggTas2r), and turkey (mgTas2r) bitter taste receptors are listed. The signal amplitudes are divided in 3 categories, weak (Inline graphic, ΔF/F < 0.2), medium (Inline graphic, ΔF/F 0.2–0.4), and high (Inline graphic, ΔF/F > 0.4).