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. 2023 Oct 5;7:100610. doi: 10.1016/j.crfs.2023.100610

Table 1.

Experimental design of response surface methodology with factors and their levels.

Independent factors Units Levels
Low (−1) Medium (0) High (1)
X1: Ethanol concentration % 70 80 90
X2: Extraction time h 2 4 6
X3: Solid-to-liquid ratio g/v 1:15 1:18 1:21