TABLE 1.

Sequence identities between the M. hominis ParC and ParE QRDRs and homologous regions of ParC, GyrA, ParE, and GyrB from various species^a

M. hominis protein	% Amino acid identity
	M. genitalium				B. subtilis				S. aureus				S. pneumoniae		E. coli
	ParC	ParE	GyrA	GyrB	GrlA	GrlB	GyrA	GyrB	GrlA	GrlB	GyrA	GyrB	ParC	ParE	ParC	ParE	GyrA	GyrB
ParC	62		55		64		60		62		59		61		57.5		53
ParE		59		51.5		72		60.5		73		59.5		77		46.5		53.5

^aThe data shown are from the following references: M. genitalium, 10; B. subtilis, 22 and 27, S. aureus, 9 and 21; S. pneumoniae, 24; E. coli, 1, 18, and 30. The ParC and GyrA sequences correspond to residues 36 to 181 and 39 to 183 of E. coli ParC and GyrA, respectively. The ParE and GyrB sequences correspond to residues 397 to 494 and 403 to 502 of E. coli ParE and GyrB, respectively.