Table 2.

Brain regions with the highest predictive scores for response to neurostimulation combined with cognitive stimulation in AD patients.

Brain region	Average amplitude (μV)	Feature importance
Frontal	<= 0.959	0.074
Central/parietal	<= 0.995	0.069
Temporal	<= 0.995	0.022
Occipital	<= 1.02	0.051

Average amplitudes refer to the mean of the patterns or oscillations of electrical brain activity at different frequencies (delta, theta, alpha, beta, and gamma) for each brain region. Feature importance corresponds to the frequency of the brain region’s appearance across all trees. The range of feature importance values in a Random Forest can vary from 0 to 1, with higher values indicating greater importance and being considered more influential in making accurate predictions.