Table 4.

Incidence of treatment-related adverse events

	Any grade	Grade 3–4
Alopecia	1 (3.2)	0
Anemia	0	1 (3.2)
Anorexia	5 (16.1)	0
Arrhythmia	1 (3.2)	0
Bleeding	2 (6.5)	0
Constipation	2 (6.5)	1 (3.2)
Cough	1 (3.2)	0
Diarrhea	4 (12.9)	0
Dyspnea	4 (12.9)	0
Electrolyte imbalance	6 (19.4)	2 (6.5)
Elevated amylase/lipase	1 (3.2)	0
Epigastric pain	1 (3.2)	0
Fatigue	2 (3.2)	0
Fever	3 (9.7)	0
Headache	2 (6.5)	0
Hyperglycemia	1 (3.2)	1 (3.2)
Hypothyroidism	4 (12.9)	0
Insomnia	3 (9.7)	0
Infusion-related reaction	4 (12.9)	0
Intraocular problem	1 (3.2)	0
Otitis	1 (3.2)	0
Pneumonia	5 (16.1)	1 (3.2)
Pruritus	3 (9.7)	0
Nausea	5 (16.1)	0
Rash	6 (19.4)	0
Seizure	1 (3.2)	0
Stomatitis	4 (12.9)	0
Thrombosis	1 (3.2)	0
Worsening of cancer pain	2 (6.5)	0

Values are presented as number (%).