Table 3.
Characteristics of genetic variants related to adult height from generalized multifactor dimensionality reduction analysis.
| CHR1 | SNP2 | Base pair | A13 | A24 | OR5 | SE6 | p for city7 | p for asan+nong8 | MAF9 | P for HWE10 | Gene names | Location |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 7 | rs146148222 | 80,304,855 | G | C | 0.8192 | 0.02823 | 1.64E-12 | 3.35E-05 | 0.0702 | 0.8087 | CD36 | Intron |
| 8 | rs325 | 19,819,328 | C | T | 0.7257 | 0.02239 | 1.68E-46 | 2.41E-11 | 0.1249 | 0.3452 | LPL | Intron |
| 9 | rs1883025 | 107,664,301 | T | C | 1.218 | 0.01593 | 3.26E-35 | 7.17E-07 | 0.2508 | 0.8261 | ABCA1 | Intron |
| 11 | rs180327 | 116,623,659 | C | T | 1.164 | 0.0141 | 3.7E-27 | 9.45E-09 | 0.4312 | 0.2257 | BUD13 | Intron |
| 11 | rs3741297 | 116,657,667 | T | C | 1.887 | 0.02421 | 1.1E-151 | 7.80E-16 | 0.0797 | 0.1767 | ZPR1 | Intron |
| 11 | rs5069 | 116,708,254 | A | G | 0.7417 | 0.03244 | 4.11E-13 | 4.42E-05 | 0.0541 | 0.936 | APOA1 | 5’-UTR |
| 11 | rs7115583 | 11,678,437 | T | G | 0.8182 | 0.02029 | 4.61E-23 | 1.12E-06 | 0.1489 | 0.4839 | SIK3 | Intron |
| 15 | rs588136 | 58,730,498 | C | T | 0.819 | 0.01455 | 7.29E-43 | 1.33E-12 | 0.3930 | 0.869 | ALDH1A2 | Intron |
| 16 | rs708272 | 56,996,288 | A | G | 0.7472 | 0.01473 | 4.14E-87 | 6.74E-10 | 0.3816 | 0.1618 | CETP | Intron |
| 19 | rs429358 (cys130arg) | 45,411,941 | C | T | 1.309 | 0.02316 | 3.03E-31 | 2.74E-11 | 0.0956 | 0.5349 | APOE | Missense |
1Chromosome; 2Single nucleotide polymorphism; 3Minor allele; 4Major allele5Odds ratio (OR) for city cohort; 6Standard error; 7P-value for OR after adjusting for age, gender, residence area, survey year, body mass index, daily energy intake, education and income in the hospital-based cohort (case: n = 17,545; control: n = 36,283); 8P-value for OR after adjusting for covariates in the Ansan/Ansung cohort (case: n = 1,657; control: n = 3,245); 9Minor allele frequency; 10Hardy-Weinberg equilibrium.