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. 2023 Oct 4;10:1264921. doi: 10.3389/fcvm.2023.1264921

Table 3.

Univariate linear regression results for children's arterial intima-media thickness.

Common carotid artery IMT Brachial artery IMT Radial artery IMT Femoral artery IMT
B (95% CI) Standβ R 2 p B (95% CI) Standβ R 2 p B (95% CI) Standβ R 2 p B (95% CI) Standβ R 2 p
Sex (0 = female, 1 = male) 12.03 (−0.70 to 24.77) 0.114 0.013 0.064 10.38 (5.85 to 14.91) 0.268 0.072 <0.001 8.69 (3.88 to 13.50) 0.215 0.046 <0.001 7.12 (−0.91 to 15.15) 0.107 0.011 0.082
Age (years) −0.03 (−5.82 to 5.75) −0.001 0.000 0.991 2.12 (0.01 to 4.22) 0.121 0.015 0.049 6.11 (4.02 to 8.20) 0.335 0.112 <0.001 6.03 (2.46 to 9.61) 0.201 0.040 0.001
Anthropometrics
Body height (cm) 0.96 (0.30 to 1.62) 0.174 0.030 0.004 0.61 (0.38 to 0.85) 0.304 0.092 <0.001 0.80 (0.56 to 1.03) 0.378 0.143 <0.001 1.24 (0.85 to 1.63) 0.357 0.127 <0.001
Height z-score 11.62 (5.62 to 17.16) 0.229 0.052 <0.001 5.54 (3.38 to 7.69) 0.298 0.089 <0.001 3.81 (1.50 to 6.13) 0.197 0.039 0.001 9.31 (5.60 to 13.02) 0.291 0.085 <0.001
Body weight (kg) 0.45 (−0.12 to 1.02) 0.096 0.009 0.118 0.53 (0.34 to 0.73) 0.310 0.096 <0.001 0.38 (0.16 to 0.59) 0.209 0.044 <0.001 0.93 (0.59 to 1.28) 0.315 0.099 <0.001
Weight z-score (age) 7.72 (1.55 to 13.88) 0.150 0.022 0.014 5.53 (3.35 to 7.72) 0.294 0.086 <0.001 1.28 (−1.10 to 3.66) 0.065 0.004 0.292 9.27 (5.50 to 13.04) 0.286 0.082 <0.001
Body surface area (m2) 29.89 (−0.24 to 60.02) 0.119 0.014 0.052 29.32 (18.79 to 39.86) 0.320 0.102 <0.001 23.43 (12.15 to 34.70) 0.245 0.060 <0.001 53.52 (35.54 to 71.50) 0.339 0.115 <0.001
Lean body mass (kg) 1.15 (0.22 to 2.09) 0.148 0.022 0.016 0.99 (0.67 to 1.32) 0.352 0.124 <0.001 1.13 (0.79 to 1.46) 0.380 0.144 <0.001 1.90 (1.35 to 2.45) 0.384 0.148 <0.001
Skeletal muscle mass (kg) 1.98 (0.41 to 3.56) 0.151 0.023 0.014 1.70 (1.16 to 2.24) 0.357 0.128 <0.001 1.93 (1.36 to 2.49) 0.385 0.148 <0.001 3.19 (2.25 to 4.12) 0.383 0.146 <0.001
Head circumf (cm) 5.00 (1.25 to 8.76) 0.163 0.027 0.009 2.65 (1.29 to 4.00) 0.236 0.055 <0.001 1.97 (0.54 to 3.39) 0.170 0.029 0.007 4.63 (2.33 to 6.92) 0.242 0.059 <0.001
Thoracic circumf (cm) 0.92 (−0.04 to 1.87) 0.118 0.014 0.060 0.93 (0.60 to 1.26) 0.328 0.108 <0.001 0.38 (0.02 to 0.75) 0.131 0.017 0.038 1.18 (0.60 to 1.76) 0.244 0.060 <0.001
Hip circumf (cm) 0.37 (−0.35 to 1.10) 0.062 0.004 0.311 0.62 (0.36 to 0.87) 0.283 0.080 <0.001 0.31 (0.03 to 0.58) 0.136 0.018 0.028 1.15 (0.71 to 1.58) 0.306 0.093 <0.001
Brachial circumf (cm) 1.55 (−0.49 to 3.59) 0.093 0.009 0.137 1.43 (0.70 to 2.15) 0.236 0.056 <0.001 0.47 (−0.31 to 1.25) 0.075 0.006 0.233 2.54 (1.31 to 3.77) 0.247 0.061 <0.001
Antebrach circumf (cm) 3.99 (0.95 to 7.03) 0.160 0.026 0.010 2.19 (1.10 to 3.28) 0.241 0.058 <0.001 0.52 (−0.65 to 1.70) 0.055 0.003 0.380 3.99 (2.14 to 5.84) 0.258 0.067 <0.001
Arm length (cm) 2.60 (0.83 to 4.37) 0.179 0.032 0.004 1.59 (0.96 to 2.21) 0.299 0.090 <0.001 1.80 (1.15 to 2.45) 0.326 0.106 <0.001 2.75 (1.69 to 3.81) 0.305 0.093 <0.001
Thigh circumf (cm) 0.15 (−0.99 to 1.29) 0.016 0.000 0.798 0.57 (0.16 to 0.98) 0.170 0.029 0.006 0.21 (−0.22 to 0.65) 0.061 0.004 0.333 1.39 (0.71 to 2.07) 0.243 0.059 <0.001
Calf circumf (cm) 0.58 (−1.40 to 2.57) 0.036 0.001 0.563 1.54 (0.85 to 2.24) 0.264 0.070 <0.001 0.75 (0 to 1.50) 0.123 0.015 0.050 2.73 (1.55 to 3.91) 0.274 0.075 <0.001
Leg length (cm) 0.80 (−0.17 to 1.76) 0.102 0.010 0.104 0.65 (0.30 to 0.99) 0.226 0.051 <0.001 0.84 (0.48 to 1.19) 0.282 0.079 <0.001 1.38 (0.80 to 1.95) 0.284 0.081 <0.001
Adiposity
Waist–hip ratio (no unit) −40.58 (−154.41 to 73.25) −0.043 0.002 0.483 54.81 (13.59 to 96.03) 0.159 0.025 0.009 5.19 (−38.51 to 48.89) 0.014 0.000 0.815 34.04 (−37.62 to 105.70) 0.057 0.003 0.350
BMI (kg/m2) 0.39 (−1.52 to 2.31) 0.025 0.001 0.687 1.35 (0.67 to 2.03) 0.233 0.054 <0.001 0.17 (−0.56 to 0.90) 0.028 0.001 0.648 2.06 (0.88 to 3.24) 0.206 0.043 <0.001
BMI z-score 3.38 (−2.73 to 9.49) 0.067 0.004 0.277 3.86 (1.67 to 6.06) 0.209 0.044 <0.001 −0.47 (−2.81 to 1.88) −0.024 0.001 0.695 6.89 (3.12 to 10.65) 0.216 0.047 <0.001
Fat mass (kg) −0.02 (−1.05 to 1.01) −0.002 0.000 0.972 0.52 (0.15 to 0.89) 0.168 0.028 0.006 −0.13 (−0.52 to 0.27) −0.039 0.002 0.529 0.82 (0.17 to 1.46) 0.152 0.023 0.013
Fat percentage (%) −0.12 (−0.85 to 0.62) −0.019 0.000 0.755 0.16 (−0.11 to 0.42) 0.072 0.005 0.243 −0.39 (−0.67 to −0.12) −0.171 0.029 0.006 0.35 (−0.11 to 0.82) 0.092 0.008 0.136
Ambulatory BP (mmHg)
24 h SBP 0.31 (−0.56 to 1.18) 0.049 0.002 0.480 0.45 (0.14 to 0.77) 0.193 0.037 0.005 0.45 (0.12 to 0.79) 0.183 0.033 0.009 0.90 (0.36 to 1.44) 0.222 0.049 0.001
24 h DBP 0.19 (−1.10 to 1.48) 0.020 0.000 0.773 −0.23 (−0.70 to 0.25) −0.066 0.004 0.349 0.21 (−0.29 to 0.72) 0.058 0.003 0.406 0.08 (−0.75 to 0.90) 0.013 0.000 0.857
24 h PP 0.34 (−0.68 to 1.36) 0.046 0.002 0.514 0.73 (0.37 to 1.09) 0.267 0.071 <0.001 0.49 (0.09 to 0.88) 0.166 0.028 0.017 1.16 (0.53 to 1.80) 0.245 0.060 <0.001
Daytime SBP 0.23 (−0.59 to 1.04) 0.036 0.001 0.586 0.35 (0.06 to 0.64) 0.157 0.025 0.019 0.46 (0.14 to 0.77) 0.190 0.036 0.004 0.71 (0.20 to 1.21) 0.182 0.033 0.006
Daytime DBP 0.03 (−1.11 to 1.17) 0.004 0.000 0.957 −0.14 (−0.55 to 0.27) −0.045 0.002 0.507 0.25 (−0.19 to 0.69) 0.074 0.006 0.268 0.08 (−0.64 to 0.79) 0.014 0.000 0.830
Daytime PP 0.37 (−0.65 to 1.39) 0.048 0.002 0.474 0.67 (0.31 to 1.02) 0.241 0.058 <0.001 0.51 (0.12 to 0.90) 0.169 0.029 0.011 1.03 (0.41 to 1.65) 0.213 0.045 0.001
Nighttime SBP 0.26 (−0.43 to 0.96) 0.051 0.003 0.452 0.30 (0.06 to 0.55) 0.160 0.026 0.017 0.28 (0.01 to 0.55) 0.139 0.019 0.039 0.56 (0.13 to 0.99) 0.170 0.029 0.011
Nighttime DBP −0.02 (−1.00 to 0.95) −0.003 0.000 0.964 −0.28 (−0.63 to 0.07) −0.105 0.011 0.118 0.03 (−0.35 to 0.40) 0.009 0.000 0.889 −0.18 (−0.79 to 0.44) −0.038 0.001 0.571
Nighttime PP 0.23 (−0.61 to 1.07) 0.036 0.001 0.591 0.69 (0.40 to 0.98) 0.303 0.092 <0.001 0.38 (0.06 to 0.70) 0.156 0.024 0.021 1.05 (0.54 to 1.56) 0.263 0.069 <0.001
PWV
Carotid–femoral PWV (m/s) −2.68 (−11.28 to 5.92) −0.039 0.002 0.540 2.79 (−0.38 to 5.95) 0.110 0.012 0.084 7.55 (4.37 to 10.73) 0.284 0.081 <0.001 6.42 (1.15 to 11.70) 0.150 0.023 0.017
Carotid–radial PWV (m/s) 2.03 (−3.63 to 7.69) 0.045 0.002 0.481 1.41 (−0.68 to 3.50) 0.084 0.007 0.184 3.02 (0.87 to 5.17) 0.173 0.030 0.006 1.13 (−2.37 to 4.64) 0.040 0.002 0.525
Central SBP (mmHg) 0.35 (−0.21 to 0.92) 0.077 0.006 0.222 0.31 (0.11 to 0.52) 0.187 0.035 0.003 0.45 (0.24 to 0.66) 0.256 0.066 <0.001 0.50 (0.15 to 0.85) 0.177 0.031 0.005
Central DBP (mmHg) 0.34 (−0.75 to 1.42) 0.039 0.001 0.543 0.10 (−0.30 to 0.50) 0.031 0.001 0.620 0.34 (−0.07 to 0.76) 0.103 0.011 0.105 0.31 (−0.36 to 0.98) 0.057 0.003 0.364
Central PP (mmHg) 0.28 (−0.31 to 0.87) 0.060 0.004 0.345 0.31 (0.10 to 0.52) 0.177 0.031 0.005 0.38 (0.16 to 0.61) 0.210 0.044 <0.001 0.45 (0.09 to 0.81) 0.152 0.023 0.015

B, unstandardized beta; Standβ, standardized beta; 95% CI, 95% confidence interval; R2, non-adjusted R square; circumf, circumference.

The unstandardized coefficients (and 95% CIs) have been multiplied by 1,000, showing the change in micrometers.

Significant p-values (<0.01) are in bold.