Table 3.
Univariate linear regression results for children's arterial intima-media thickness.
Common carotid artery IMT | Brachial artery IMT | Radial artery IMT | Femoral artery IMT | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B (95% CI) | Standβ | R 2 | p | B (95% CI) | Standβ | R 2 | p | B (95% CI) | Standβ | R 2 | p | B (95% CI) | Standβ | R 2 | p | |
Sex (0 = female, 1 = male) | 12.03 (−0.70 to 24.77) | 0.114 | 0.013 | 0.064 | 10.38 (5.85 to 14.91) | 0.268 | 0.072 | <0.001 | 8.69 (3.88 to 13.50) | 0.215 | 0.046 | <0.001 | 7.12 (−0.91 to 15.15) | 0.107 | 0.011 | 0.082 |
Age (years) | −0.03 (−5.82 to 5.75) | −0.001 | 0.000 | 0.991 | 2.12 (0.01 to 4.22) | 0.121 | 0.015 | 0.049 | 6.11 (4.02 to 8.20) | 0.335 | 0.112 | <0.001 | 6.03 (2.46 to 9.61) | 0.201 | 0.040 | 0.001 |
Anthropometrics | ||||||||||||||||
Body height (cm) | 0.96 (0.30 to 1.62) | 0.174 | 0.030 | 0.004 | 0.61 (0.38 to 0.85) | 0.304 | 0.092 | <0.001 | 0.80 (0.56 to 1.03) | 0.378 | 0.143 | <0.001 | 1.24 (0.85 to 1.63) | 0.357 | 0.127 | <0.001 |
Height z-score | 11.62 (5.62 to 17.16) | 0.229 | 0.052 | <0.001 | 5.54 (3.38 to 7.69) | 0.298 | 0.089 | <0.001 | 3.81 (1.50 to 6.13) | 0.197 | 0.039 | 0.001 | 9.31 (5.60 to 13.02) | 0.291 | 0.085 | <0.001 |
Body weight (kg) | 0.45 (−0.12 to 1.02) | 0.096 | 0.009 | 0.118 | 0.53 (0.34 to 0.73) | 0.310 | 0.096 | <0.001 | 0.38 (0.16 to 0.59) | 0.209 | 0.044 | <0.001 | 0.93 (0.59 to 1.28) | 0.315 | 0.099 | <0.001 |
Weight z-score (age) | 7.72 (1.55 to 13.88) | 0.150 | 0.022 | 0.014 | 5.53 (3.35 to 7.72) | 0.294 | 0.086 | <0.001 | 1.28 (−1.10 to 3.66) | 0.065 | 0.004 | 0.292 | 9.27 (5.50 to 13.04) | 0.286 | 0.082 | <0.001 |
Body surface area (m2) | 29.89 (−0.24 to 60.02) | 0.119 | 0.014 | 0.052 | 29.32 (18.79 to 39.86) | 0.320 | 0.102 | <0.001 | 23.43 (12.15 to 34.70) | 0.245 | 0.060 | <0.001 | 53.52 (35.54 to 71.50) | 0.339 | 0.115 | <0.001 |
Lean body mass (kg) | 1.15 (0.22 to 2.09) | 0.148 | 0.022 | 0.016 | 0.99 (0.67 to 1.32) | 0.352 | 0.124 | <0.001 | 1.13 (0.79 to 1.46) | 0.380 | 0.144 | <0.001 | 1.90 (1.35 to 2.45) | 0.384 | 0.148 | <0.001 |
Skeletal muscle mass (kg) | 1.98 (0.41 to 3.56) | 0.151 | 0.023 | 0.014 | 1.70 (1.16 to 2.24) | 0.357 | 0.128 | <0.001 | 1.93 (1.36 to 2.49) | 0.385 | 0.148 | <0.001 | 3.19 (2.25 to 4.12) | 0.383 | 0.146 | <0.001 |
Head circumf (cm) | 5.00 (1.25 to 8.76) | 0.163 | 0.027 | 0.009 | 2.65 (1.29 to 4.00) | 0.236 | 0.055 | <0.001 | 1.97 (0.54 to 3.39) | 0.170 | 0.029 | 0.007 | 4.63 (2.33 to 6.92) | 0.242 | 0.059 | <0.001 |
Thoracic circumf (cm) | 0.92 (−0.04 to 1.87) | 0.118 | 0.014 | 0.060 | 0.93 (0.60 to 1.26) | 0.328 | 0.108 | <0.001 | 0.38 (0.02 to 0.75) | 0.131 | 0.017 | 0.038 | 1.18 (0.60 to 1.76) | 0.244 | 0.060 | <0.001 |
Hip circumf (cm) | 0.37 (−0.35 to 1.10) | 0.062 | 0.004 | 0.311 | 0.62 (0.36 to 0.87) | 0.283 | 0.080 | <0.001 | 0.31 (0.03 to 0.58) | 0.136 | 0.018 | 0.028 | 1.15 (0.71 to 1.58) | 0.306 | 0.093 | <0.001 |
Brachial circumf (cm) | 1.55 (−0.49 to 3.59) | 0.093 | 0.009 | 0.137 | 1.43 (0.70 to 2.15) | 0.236 | 0.056 | <0.001 | 0.47 (−0.31 to 1.25) | 0.075 | 0.006 | 0.233 | 2.54 (1.31 to 3.77) | 0.247 | 0.061 | <0.001 |
Antebrach circumf (cm) | 3.99 (0.95 to 7.03) | 0.160 | 0.026 | 0.010 | 2.19 (1.10 to 3.28) | 0.241 | 0.058 | <0.001 | 0.52 (−0.65 to 1.70) | 0.055 | 0.003 | 0.380 | 3.99 (2.14 to 5.84) | 0.258 | 0.067 | <0.001 |
Arm length (cm) | 2.60 (0.83 to 4.37) | 0.179 | 0.032 | 0.004 | 1.59 (0.96 to 2.21) | 0.299 | 0.090 | <0.001 | 1.80 (1.15 to 2.45) | 0.326 | 0.106 | <0.001 | 2.75 (1.69 to 3.81) | 0.305 | 0.093 | <0.001 |
Thigh circumf (cm) | 0.15 (−0.99 to 1.29) | 0.016 | 0.000 | 0.798 | 0.57 (0.16 to 0.98) | 0.170 | 0.029 | 0.006 | 0.21 (−0.22 to 0.65) | 0.061 | 0.004 | 0.333 | 1.39 (0.71 to 2.07) | 0.243 | 0.059 | <0.001 |
Calf circumf (cm) | 0.58 (−1.40 to 2.57) | 0.036 | 0.001 | 0.563 | 1.54 (0.85 to 2.24) | 0.264 | 0.070 | <0.001 | 0.75 (0 to 1.50) | 0.123 | 0.015 | 0.050 | 2.73 (1.55 to 3.91) | 0.274 | 0.075 | <0.001 |
Leg length (cm) | 0.80 (−0.17 to 1.76) | 0.102 | 0.010 | 0.104 | 0.65 (0.30 to 0.99) | 0.226 | 0.051 | <0.001 | 0.84 (0.48 to 1.19) | 0.282 | 0.079 | <0.001 | 1.38 (0.80 to 1.95) | 0.284 | 0.081 | <0.001 |
Adiposity | ||||||||||||||||
Waist–hip ratio (no unit) | −40.58 (−154.41 to 73.25) | −0.043 | 0.002 | 0.483 | 54.81 (13.59 to 96.03) | 0.159 | 0.025 | 0.009 | 5.19 (−38.51 to 48.89) | 0.014 | 0.000 | 0.815 | 34.04 (−37.62 to 105.70) | 0.057 | 0.003 | 0.350 |
BMI (kg/m2) | 0.39 (−1.52 to 2.31) | 0.025 | 0.001 | 0.687 | 1.35 (0.67 to 2.03) | 0.233 | 0.054 | <0.001 | 0.17 (−0.56 to 0.90) | 0.028 | 0.001 | 0.648 | 2.06 (0.88 to 3.24) | 0.206 | 0.043 | <0.001 |
BMI z-score | 3.38 (−2.73 to 9.49) | 0.067 | 0.004 | 0.277 | 3.86 (1.67 to 6.06) | 0.209 | 0.044 | <0.001 | −0.47 (−2.81 to 1.88) | −0.024 | 0.001 | 0.695 | 6.89 (3.12 to 10.65) | 0.216 | 0.047 | <0.001 |
Fat mass (kg) | −0.02 (−1.05 to 1.01) | −0.002 | 0.000 | 0.972 | 0.52 (0.15 to 0.89) | 0.168 | 0.028 | 0.006 | −0.13 (−0.52 to 0.27) | −0.039 | 0.002 | 0.529 | 0.82 (0.17 to 1.46) | 0.152 | 0.023 | 0.013 |
Fat percentage (%) | −0.12 (−0.85 to 0.62) | −0.019 | 0.000 | 0.755 | 0.16 (−0.11 to 0.42) | 0.072 | 0.005 | 0.243 | −0.39 (−0.67 to −0.12) | −0.171 | 0.029 | 0.006 | 0.35 (−0.11 to 0.82) | 0.092 | 0.008 | 0.136 |
Ambulatory BP (mmHg) | ||||||||||||||||
24 h SBP | 0.31 (−0.56 to 1.18) | 0.049 | 0.002 | 0.480 | 0.45 (0.14 to 0.77) | 0.193 | 0.037 | 0.005 | 0.45 (0.12 to 0.79) | 0.183 | 0.033 | 0.009 | 0.90 (0.36 to 1.44) | 0.222 | 0.049 | 0.001 |
24 h DBP | 0.19 (−1.10 to 1.48) | 0.020 | 0.000 | 0.773 | −0.23 (−0.70 to 0.25) | −0.066 | 0.004 | 0.349 | 0.21 (−0.29 to 0.72) | 0.058 | 0.003 | 0.406 | 0.08 (−0.75 to 0.90) | 0.013 | 0.000 | 0.857 |
24 h PP | 0.34 (−0.68 to 1.36) | 0.046 | 0.002 | 0.514 | 0.73 (0.37 to 1.09) | 0.267 | 0.071 | <0.001 | 0.49 (0.09 to 0.88) | 0.166 | 0.028 | 0.017 | 1.16 (0.53 to 1.80) | 0.245 | 0.060 | <0.001 |
Daytime SBP | 0.23 (−0.59 to 1.04) | 0.036 | 0.001 | 0.586 | 0.35 (0.06 to 0.64) | 0.157 | 0.025 | 0.019 | 0.46 (0.14 to 0.77) | 0.190 | 0.036 | 0.004 | 0.71 (0.20 to 1.21) | 0.182 | 0.033 | 0.006 |
Daytime DBP | 0.03 (−1.11 to 1.17) | 0.004 | 0.000 | 0.957 | −0.14 (−0.55 to 0.27) | −0.045 | 0.002 | 0.507 | 0.25 (−0.19 to 0.69) | 0.074 | 0.006 | 0.268 | 0.08 (−0.64 to 0.79) | 0.014 | 0.000 | 0.830 |
Daytime PP | 0.37 (−0.65 to 1.39) | 0.048 | 0.002 | 0.474 | 0.67 (0.31 to 1.02) | 0.241 | 0.058 | <0.001 | 0.51 (0.12 to 0.90) | 0.169 | 0.029 | 0.011 | 1.03 (0.41 to 1.65) | 0.213 | 0.045 | 0.001 |
Nighttime SBP | 0.26 (−0.43 to 0.96) | 0.051 | 0.003 | 0.452 | 0.30 (0.06 to 0.55) | 0.160 | 0.026 | 0.017 | 0.28 (0.01 to 0.55) | 0.139 | 0.019 | 0.039 | 0.56 (0.13 to 0.99) | 0.170 | 0.029 | 0.011 |
Nighttime DBP | −0.02 (−1.00 to 0.95) | −0.003 | 0.000 | 0.964 | −0.28 (−0.63 to 0.07) | −0.105 | 0.011 | 0.118 | 0.03 (−0.35 to 0.40) | 0.009 | 0.000 | 0.889 | −0.18 (−0.79 to 0.44) | −0.038 | 0.001 | 0.571 |
Nighttime PP | 0.23 (−0.61 to 1.07) | 0.036 | 0.001 | 0.591 | 0.69 (0.40 to 0.98) | 0.303 | 0.092 | <0.001 | 0.38 (0.06 to 0.70) | 0.156 | 0.024 | 0.021 | 1.05 (0.54 to 1.56) | 0.263 | 0.069 | <0.001 |
PWV | ||||||||||||||||
Carotid–femoral PWV (m/s) | −2.68 (−11.28 to 5.92) | −0.039 | 0.002 | 0.540 | 2.79 (−0.38 to 5.95) | 0.110 | 0.012 | 0.084 | 7.55 (4.37 to 10.73) | 0.284 | 0.081 | <0.001 | 6.42 (1.15 to 11.70) | 0.150 | 0.023 | 0.017 |
Carotid–radial PWV (m/s) | 2.03 (−3.63 to 7.69) | 0.045 | 0.002 | 0.481 | 1.41 (−0.68 to 3.50) | 0.084 | 0.007 | 0.184 | 3.02 (0.87 to 5.17) | 0.173 | 0.030 | 0.006 | 1.13 (−2.37 to 4.64) | 0.040 | 0.002 | 0.525 |
Central SBP (mmHg) | 0.35 (−0.21 to 0.92) | 0.077 | 0.006 | 0.222 | 0.31 (0.11 to 0.52) | 0.187 | 0.035 | 0.003 | 0.45 (0.24 to 0.66) | 0.256 | 0.066 | <0.001 | 0.50 (0.15 to 0.85) | 0.177 | 0.031 | 0.005 |
Central DBP (mmHg) | 0.34 (−0.75 to 1.42) | 0.039 | 0.001 | 0.543 | 0.10 (−0.30 to 0.50) | 0.031 | 0.001 | 0.620 | 0.34 (−0.07 to 0.76) | 0.103 | 0.011 | 0.105 | 0.31 (−0.36 to 0.98) | 0.057 | 0.003 | 0.364 |
Central PP (mmHg) | 0.28 (−0.31 to 0.87) | 0.060 | 0.004 | 0.345 | 0.31 (0.10 to 0.52) | 0.177 | 0.031 | 0.005 | 0.38 (0.16 to 0.61) | 0.210 | 0.044 | <0.001 | 0.45 (0.09 to 0.81) | 0.152 | 0.023 | 0.015 |
B, unstandardized beta; Standβ, standardized beta; 95% CI, 95% confidence interval; R2, non-adjusted R square; circumf, circumference.
The unstandardized coefficients (and 95% CIs) have been multiplied by 1,000, showing the change in micrometers.
Significant p-values (<0.01) are in bold.