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. 2023 Oct 4;14:1267445. doi: 10.3389/fphar.2023.1267445

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Copyright © 2023 Wang, Bai, Li, Liu, Wang, Ju, Yao, Xiong and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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scRNA-Seq analysis of liver cells from HFD + Veh or HFD + Gink groups. (A) UMAP plot revealed that the liver cells were divided into 10 clusters based on marker genes. (B) UMAP plot for liver cells from HFD + Veh and HFD + Gink groups. (C) marker gene expression for the 10 clusters shown by violin plots. (D) Top 10 marker genes of the 10 clusters shown by heatmap. (E) Cell percent of the 10 clusters in each sample. (F) Cell counts of the 10 clusters in the two groups. (G) Changes in gene expression by ginkgetin in the 10 clusters between HFD + Veh and HFD + Gink groups.