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. 2023 Oct 4;14:1219785. doi: 10.3389/fimmu.2023.1219785

Figure 5.

Figure 5

(A) PpIX-1MT chimeric peptide nanoparticles target tumor areas via the EPR effect, activate CD8+ T cells through cascade activations, and effectively inhibit primary tumors and lung metastasis while enabling in situ PDT to trigger apoptosis and caspase-3 production (75). Copyright 2018, American Chemical Society. (B) Illustration of NIR light-mediated PDT strategy for the enhanced cellular ablation in tumor microenvironment (76). Copyright 2018, American Chemical Society.