Table 1.

Summary of nanomaterials in the combination of PDT with immune checkpoint.

Nanomaterial	PS drug	Nanotechn-ology	Immuno-therapy targeting	Experim-ent	Tumor	Anti-meta-static	Imm-une-mem-ory	Ref.
NCP@pyrolipid	pyrolipid	nanoscale coordination polymer	PD-L1	vitro+vivo	colon	√	–	(36)
IDOi@TBC-Hf	TBC-Hf	nMOF	IDO(NLG919)	vivo	colon	√	–	(100)
DSAB-HK	phthalocyanine	dye-labeled probe	PD-1	vitro+vivo	breast	√	–	(94)
ZnP@pyro	pyrolipid	ZnP@pyro	PD-L1	vitro+vivo	breast	√	–	(45)
H-MnO2-PEG/C&D	Ce6	H-MnO2	PD-L1	vivo	breast	√	–	(46)
UCNP-Ce6-R837	Ce6	UCNPs	CTLA-4	vitro+vivo	colon	√	√	(83)
PpIX-1MT	PpIX	DEVD	IDO(1MT)	vitro+vivo	colon	√	√	(75)
PpIX-NLG@Lipo	protoporphyrin IX	liposome	IDO(NLG919)	vitro+vivo	breast	√	–	(53)
BMS-202 NPs	Ce6	reprecipitation	PD-1/PD-L1(BMS-202)	vivo	breast	√	√	(99)
Chloringlobulin	Ce6	Immunoglobu-lin G	PD-L1/CTLA-4	vitro+vivo	colon	√	√	(101)
IRD-αCD276/Fab	IRDye700	Fab preparation kit	PD-L1	vitro+vivo	breast	√	–	(99)
M-MONs@Ce6	Ce6	organosilica	CTLA-4	vitro+vivo	breast	√	–	(51)
Ce6@liposome-based	Ce6	liposome、DEX-Haase	PD-L1	vitro+vivo	breast	√	–	(102)
FIC	Ce6	–	PD-L1	vitro+vivo	Melan-oma/ colon	√	–	(103)
HS201-PDT	HS201	heat shock protein 90	PD-L1	vitro+vivo	breast	√	–	(104)