Table 2.

Summary of nanomaterials in the combination of PDT with cancer vaccine.

Nanomate-rial	Vaccine platform type	Autol-ogous or alloge-neic	Antig-en	PS drug	Immune expression	Immune-memory	Ref
PC-Cell@gel	Cellbased (tumor cell)	Autol-ogous	–	PEI-CE6	TAAs, mDC, CD8+↑ Treg↓	√	(111)
PDT-based DCvaccine	Cellbased (DC)	Autol-ogous	–	OR141	TAAs, CD8+, CD4+, IFN-γ↑	√	(112)
ALA-PDT-DC	Cellbased (DC)	Autol-ogous	–	ALA	TAAs, IFN-γ, TNF-α, CTL, mDC↑ IL-10↓	√	(113)
Lipo-PhA	Protein	Allog-eneic	FlaB-Vax	Lipo-PhA	TAAs, CTL, IFN γ↑	√	(93)
nMOF	DNA vaccine	Allog-eneic	CpG	H2TCPP	TAAs, IFN-γ, TNF-α, CTL, mDC↑	√	(54)
SPNI	Protein	Allog-eneic	TLR7	Semico-nducting polymer	TAAs, CD8+, CD4+, IFN-γ↑	√	(97)

(↑, upregulation; ↓, downregulation).