Table 3.
Mixed effects models of global cognition: associations between gait-speed and gait-related deformation scores with cognitive level and change, modeled separately, and together.
| Cognitive level b, p-val, (95%CI) | Cognitive change b, p-val, (95%CI) | |||||
|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | |
| Gait speed | 0.118, p < 0.001 (0.073, 0.164) | – | 0.092, p < 0.001 (0.046, 0.138) | 0.013, p = 0.035 (9E−4, 0.025) | – | 0.004, p = 0.51 (−0.008, 0.016) |
| PC 1 | – | 0.146, p < 0.001 (0.077, 0.214) | 0.133, p < 0.001 (0.066, 0.201) | – | 0.051, p < 0.001 (0.032, 0.07) | 0.050, p < 0.001 (0.032, 0.069) |
| PC 3 | – | 0.081, p = 0.005 (0.024, 0.137) | 0.054, p = 0.06 (−0.003, 0.111) | – | 0.018, p = 0.02 (2.62E−3, 0.033) | 0.017, p = 0.04 (0.001, 0.032) |
| Explained variance | 6% | 8% | 12% | 2% | 13% | 13% |
All models were adjusted for age, sex, race, education, BMI, and their interactions with time.