Table 6.
Rates of different combinations of BRAFV600E and TERT promoter mutations in different ATA and TNM stages.
| Stage (Number of patients) | Wild BRAF/ wild TERT No. (%) |
BRAFV600E/ wild TERT No. (%) |
Wild BRAF/ Mutated TERT No. (%) |
BRAFV600E/ mutated TERT No. (%) |
P value |
|---|---|---|---|---|---|
| ATA staging | |||||
| Low-risk (96) | 39 (40.6) | 35 (36.5) | 15 (15.6) | 7 (7.3) | 0.006 |
| Intermediate risk (125) | 50 (40.0) | 53 (42.4) | 11 (8.8) | 11 (8.8) | |
| High-risk (75) | 32 (42.7) | 15 (20.0) | 12 (16) | 16 (21.3) | |
| TNM staging | |||||
| I (99) | 53 (53.5) | 43 (43.4) | 2 (2.0) | 1 (1.0) | <0.0001 |
| II (150) | 53 (35.3) | 51 (34.0) | 24 (16.0) | 22 (14.7) | |
| III (27) | 12 (44.4) | 7 (25.9) | 6 (22.2) | 2 (7.4) | |
| IV (20) | 3 (15.0) | 2 (10.0) | 6 (30) | 9 (45.0) | |